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猴痘已肆虐全球;我们是否应为新的大流行疫情爆发做好准备?

Monkeypox has devastated the world; should we prepare for the outbreak of a new pandemic?

作者信息

Awan Malik Ali Ehtsham, Waseem Maria, Sahito Areesh Fatima, Sahito Abdul Moiz, Khatri Govinda, Butt Masood Ahmed, Ramproshad Sarker, Mondal Banani, Hasan Mohammad Mehedi

机构信息

Dow University of Health Sciences, Karachi, Pakistan.

Peoples University of Medical and Health Sciences for Women (PUMHSW), Nawabshah, Pakistan.

出版信息

Ann Med Surg (Lond). 2022 Jun 23;79:104051. doi: 10.1016/j.amsu.2022.104051. eCollection 2022 Jul.

Abstract

The monkeypox virus, which belongs to the orthopoxy virus family, causes fever, lethargy, headache, lymphadenopathy, myalgia, and rash, as well as various complications such as superimposed infections, sepsis, keratitis, encephalitis, and bronchopneumonia. Following replication at the site of injection, the virus often enters by the oropharynx, nasopharynx, or intradermal pathway, spreading to lymph nodes before viremia, promoting viral dissemination to other organ systems. Monkeypox cases have recently been brought to WHO's notice from 12 presently non-endemic member nations spread over three WHO regions, with 92 laboratory-confirmed cases and 28 cases of suspicion as of May 21, 2022. Monkeypox is presently endemic in the Central African Republic, the Democratic Republic of the Congo, Benin, Cameroon, Gabon, Sierra Leone, and South Sudan. Monkeypox cases have been detected all across the world, posing a challenge to healthcare infrastructure that is still recovering from the COVID-19 outbreak. Close monitoring and exact data collecting, the implementation of successful programs across the world, and public support of preventative measures are some of the strategies being used to cope with the increasing incidence of monkeypox.

摘要

猴痘病毒属于正痘病毒科,可引起发热、乏力、头痛、淋巴结病、肌痛和皮疹,以及诸如叠加感染、败血症、角膜炎、脑炎和支气管肺炎等各种并发症。在注射部位复制后,病毒通常通过口咽、鼻咽或皮内途径进入,在病毒血症之前扩散到淋巴结,促进病毒传播到其他器官系统。最近,来自世卫组织三个区域的12个目前非流行成员国的猴痘病例已引起世卫组织的注意,截至2022年5月21日,有92例实验室确诊病例和28例疑似病例。猴痘目前在中非共和国、刚果民主共和国、贝宁、喀麦隆、加蓬、塞拉利昂和南苏丹流行。世界各地均检测到猴痘病例,这对仍在从新冠疫情中恢复的医疗基础设施构成了挑战。密切监测和准确的数据收集、在全球实施成功的项目以及公众对预防措施的支持是应对猴痘发病率上升所采用的一些策略。

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Monkeypox virus: A future scourge to the Pakistani Healthcare system.猴痘病毒:对巴基斯坦医疗系统的未来威胁。
Ann Med Surg (Lond). 2022 Jul;79:103978. doi: 10.1016/j.amsu.2022.103978. Epub 2022 Jun 11.
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Post-acute Sequelae in COVID-19 Survivors: an Overview.新冠康复者的急性后遗症概述
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