Chen Wan, Chen Hui, Mi Lan, Li Jing, Lin Haotian, Chen Weirong
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Sun Yat-sen University, Guangzhou, China.
Center for Precision Medicine, Sun Yat-sen University, Guangzhou, China.
Front Med (Lausanne). 2022 Jul 4;9:826042. doi: 10.3389/fmed.2022.826042. eCollection 2022.
To compare the effects of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) on subfoveal choroidal thickness (SFCT) in patients with age-related cataracts.
In this prospective consecutive study, 26 patients (26 eyes) with age-related cataracts without previous ocular surgery or other ocular diseases who had FLACS were included as the study group. Twenty-six age-matched patients (26 eyes) who underwent CPS in the same period were also included as the control group. The SFCT and the foveal retinal thickness (FRT) were measured at baseline and at 1 day (D1), 7 days (D7), 1 month (M1), and 3 months (M3) postoperatively by spectral-domain optical coherence tomography. Aqueous flare was also measured with a laser flare meter.
The mean SFCTs of the FLACS group at baseline and at D1, D7, M1, and M3 were 185.2, 174.3, 184.2, 180.8, and 184.1 μm, respectively. A Bonferroni posttest showed that the choroid became thinner on postoperative D1 ( = 0.006). The measurements at 1 week, 1 month, and 3 months postoperatively showed no significant differences in the SFCTs compared with that at baseline ( = 0.66, = 0.22, and = 0.53, respectively). A different trend was observed in the CPS group. The choroid became thicker by the 3-month postoperative measurement, as follows: 1 day ( = 0.28), 1 week ( = 0.016), 1 month ( = 0.020), and 3 months ( < 0.001).
The mean SFCT significantly and temporarily decreased following FLACS. In contrast, an increased SFCT was observed following CPS.
比较飞秒激光辅助白内障手术(FLACS)与传统超声乳化白内障手术(CPS)对年龄相关性白内障患者黄斑中心凹下脉络膜厚度(SFCT)的影响。
在这项前瞻性连续研究中,纳入26例(26只眼)年龄相关性白内障且既往无眼部手术史或其他眼部疾病并接受FLACS的患者作为研究组。同期纳入26例年龄匹配且接受CPS的患者(26只眼)作为对照组。术前基线以及术后1天(D1)、7天(D7)、1个月(M1)和3个月(M3)时,采用频域光学相干断层扫描测量SFCT和黄斑视网膜厚度(FRT)。同时用激光散射仪测量房水闪光。
FLACS组基线、D1、D7、M1和M3时的平均SFCT分别为185.2、174.3、184.2、180.8和184.1μm。Bonferroni事后检验显示,术后D1时脉络膜变薄(P = 0.006)。术后1周、1个月和3个月时的测量结果显示,与基线相比,SFCT无显著差异(P分别为0.66、0.22和0.53)。CPS组观察到不同的趋势。术后3个月时脉络膜增厚,具体如下:1天(P = 0.28)、1周(P = 0.016)、1个月(P = 0.020)和3个月(P < 0.001)。
FLACS后平均SFCT显著且暂时降低。相比之下,CPS后观察到SFCT增加。