Department of Pediatric Ophthalmology and Strabismus, Sadguru Netra Chikitsalya and Postgraduate Institute of Ophthalmology, Jankikund, Chitrakoot, Madhya Pradesh, India.
Department of Retina and Uvea, Sadguru Netra Chikitsalya and Postgraduate Institute of Ophthalmology, Jankikund, Chitrakoot, Madhya Pradesh, India.
Indian J Ophthalmol. 2022 Dec;70(12):4331-4336. doi: 10.4103/ijo.IJO_1114_22.
To evaluate the central macular thickness (CMT) and subfoveal choroidal thickness (SFCT) changes on spectral domain optical coherence tomography (SD-OCT) after cataract surgery with intraocular lens (IOL) implantation in a pediatric population.
This was a longitudinal, prospective, interventional study which included 90 pediatric patients who underwent cataract extraction with IOL implantation. Serial SD-OCT scans were done at postoperative day 1, 1-month, and 3-month follow-up. CMT and SFCT were measured at each visit.
A statistically significant increase in CMT was noted at 1 month (from 199.3 μm to 210.04 μm) post surgery, which declined over a 3-month period (202.70 μm, P = 0.0001). In case of SFCT, a constant increase was observed for over 3 months of follow-up (baseline: 296.52 μm; 1 month: 309.04 μm; and 3 months: 319.03 μm, P = 0.0001). The traumatic cataract group showed more pronounced changes in CMT and SFCT than the non-traumatic cataract group. No significant difference was observed regarding these parameters between those who underwent primary posterior capsulotomy (PPC) versus those who did not. None of the patients in the study group developed cystoid macular edema. These posterior segment-related anatomical changes did not affect the final visual outcomes.
Cataract surgery induces potential inflammatory changes in the macula and choroid in pediatric patients. Such changes are more pronounced in trauma-related cases; however, they are not significant enough to affect the visual outcomes. Similarly, the additional surgical step of PPC does not induce significant anatomical or functional changes.
评估儿童白内障患者行晶状体眼人工晶状体（IOL）植入术后，应用频域光学相干断层扫描（SD-OCT）检查黄斑中心厚度（CMT）和中心凹下脉络膜厚度（SFCT）的变化。
这是一项前瞻性、纵向、干预性研究，共纳入 90 例行白内障超声乳化摘除联合 IOL 植入术的儿童患者。术后第 1、1 个月和 3 个月时行 SD-OCT 检查，测量黄斑中心区和中心凹下脉络膜厚度。
术后 1 个月 CMT 显著增加（从 199.3μm 增加到 210.04μm），术后 3 个月逐渐下降（202.70μm，P=0.0001）。SFCT 在术后 3 个月持续增加（基线：296.52μm；术后 1 个月：309.04μm；术后 3 个月：319.03μm，P=0.0001）。外伤性白内障患者的 CMT 和 SFCT 改变较非外伤性白内障患者更明显。行后发性白内障切开术（PPC）和未行 PPC 的患者在这些参数方面无显著差异。研究组无患者发生囊样黄斑水肿。这些后节相关的解剖结构变化并不影响最终的视力结果。
白内障手术可导致儿童患者黄斑和脉络膜发生潜在的炎症改变。外伤性白内障患者的改变更明显，但这些改变并不足以影响视力结果。同样，PPC 这一附加手术步骤也不会引起明显的解剖或功能改变。
