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Circling In on Pulmonary Arterial Hypertension: Is It Time to Consider Circular RNA circ_0016070 as a Biomarker and Target for Therapy?

作者信息

Farkas Laszlo, Goncharova Elena A

机构信息

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Davis Heart and Lung Research Institute The Ohio State University Columbus OH.

Division of Pulmonary, Critical Care and Sleep Medicine, Lung Center University of California, Davis School of Medicine Davis CA.

出版信息

J Am Heart Assoc. 2022 Jul 19;11(14):e026798. doi: 10.1161/JAHA.122.026798. Epub 2022 Jul 8.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5833/9707829/cc0e44b36852/JAH3-11-e026798-g001.jpg

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Circular RNAs in pulmonary hypertension: Emerging biological concepts and potential mechanism.
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J Clin Invest. 2020 Nov 2;130(11):5638-5651. doi: 10.1172/JCI137558.
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Overexpression of MicroRNA-340-5p Inhibits Pulmonary Arterial Hypertension Induced by APE by Downregulating IL-1β and IL-6.
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Circular RNA hsa_circ_0016070 Is Associated with Pulmonary Arterial Hypertension by Promoting PASMC Proliferation.
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