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腹腔镜和机器人辅助输尿管肾盂成形术治疗儿童原发性和复发性肾盂输尿管交界处梗阻:与腹腔镜和机器人辅助 Anderson-Hynes 肾盂成形术的多中心对比研究。

Laparoscopic and robot-assisted ureterocalicostomy for treatment of primary and recurrent pelvi-ureteric junction obstruction in children: a multicenter comparative study with laparoscopic and robot-assisted Anderson-Hynes pyeloplasty.

机构信息

Division of Pediatric Surgery Unit, Federico II University Hospital, Via Pansini 5, 80131, Naples, Italy.

Department of Pediatric Surgery, Hôpital Universitaire Necker-Enfants Malades, Paris, France.

出版信息

Int Urol Nephrol. 2022 Oct;54(10):2503-2509. doi: 10.1007/s11255-022-03305-2. Epub 2022 Jul 21.

Abstract

PURPOSE

This multi-institutional study aimed to assess the outcomes of laparoscopic ureterocalicostomy (LUC) and robot-assisted laparoscopic ureterocalicostomy (RALUC) and compare them with laparoscopic pyeloplasty (LP) and robot-assisted laparoscopic pyeloplasty (RALP) in children with pelvi-ureteric junction obstruction (PUJO).

METHODS

The data of 130 patients (80 boys), with median age 7.6 years and median weight 33.8 kg, receiving minimally invasive treatment of PUJO over a 6-year period, were retrospectively analyzed. Patients were grouped according to the operative approach: G1 included 15 patients, receiving LUC (n = 9) and RALUC (n = 6), and G2 included 115 patients, receiving LP (n = 30) and RALP (n = 85). Patient characteristics and operative outcomes were compared in both groups.

RESULTS

The median patient age and weight were significantly higher in G1 than in G2 [p = 0.001]. The median operative time was similar in both groups (157.6 vs 150.1 min) [p = 0.66] whereas the median anastomotic time was shorter in G1 than in G2 (59.5 vs 83.1 min) [p = 0.03]. The surgical success rate was similar in both groups (100% vs 97.4%) [p = 0.33]. Post-operative complications rate was higher in G1 than in G2 (20% vs 6.1%) but all G1 complications were Clavien 2 and did not require re-intervention.

CONCLUSION

LUC/RALUC can be considered safe and effective alternative approaches to LP/RALP for PUJO repair and reported excellent outcomes as primary and salvage procedures. Robot-assisted technique was the preferred option to treat most patients with recurrent PUJO in both groups.

摘要

目的

本多机构研究旨在评估腹腔镜输尿管吻合术(LUC)和机器人辅助腹腔镜输尿管吻合术(RALUC)的治疗效果,并与腹腔镜肾盂成形术(LP)和机器人辅助腹腔镜肾盂成形术(RALP)进行比较,以评估其在治疗肾盂输尿管连接部梗阻(PUJO)患儿中的作用。

方法

回顾性分析了 6 年间接受微创治疗 PUJO 的 130 例(80 例男性)患儿的临床资料,这些患儿的中位年龄为 7.6 岁,中位体重为 33.8kg。根据手术方式将患儿分为两组:G1 组包括 15 例患儿,接受 LUC(n=9)和 RALUC(n=6)治疗;G2 组包括 115 例患儿,接受 LP(n=30)和 RALP(n=85)治疗。比较两组患儿的一般资料和手术结果。

结果

G1 组患儿的中位年龄和体重明显高于 G2 组(p=0.001)。两组患儿的中位手术时间相似(157.6 分钟比 150.1 分钟)(p=0.66),但 G1 组的中位吻合时间短于 G2 组(59.5 分钟比 83.1 分钟)(p=0.03)。两组患儿的手术成功率相似(100%比 97.4%)(p=0.33)。G1 组术后并发症发生率高于 G2 组(20%比 6.1%),但 G1 组的所有并发症均为 Clavien2 级,无需再次干预。

结论

对于治疗 PUJO,LUC/RALUC 可作为 LP/RALP 的安全有效替代方法,且无论是作为初始治疗还是挽救性治疗,其均有良好的效果。在两组患儿中,机器人辅助技术均为治疗大多数复发性 PUJO 的首选方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/404f/9463286/b30b15810917/11255_2022_3305_Fig1_HTML.jpg

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