School of Public Health, Shanghai Jiao Tong University School of Medicine, China (L.Z., Y. Wu, J.X.).
Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang (L.Z., S.L., Y.J., Y. Wang, Z.Y., Z.S.).
Hypertension. 2022 Oct;79(10):2202-2211. doi: 10.1161/HYPERTENSIONAHA.122.19568. Epub 2022 Jul 18.
Poorly controlled hypertension is a great challenge to global public health. Incentive approaches, based on behavioral and economic concepts, may improve patients' adherence to treatment.
We conducted a 2-arm randomized controlled trial to test whether financial incentives can help patients with poorly controlled hypertension in China reduce their blood pressure (BP). Participants were randomized 1:1 to the control and intervention groups. All participants received WeChat-based standard education and support for hypertension management. The intervention group received financial incentives, including process- and outcome-based incentives.
No statistically significant differences in BP reduction and hypertension control rates were found between the two groups from baseline to 12-month follow-up. Mean systolic BP decreased from 158.7 to 149.8 mm Hg in the intervention group and 159.7 to 149.5 mm Hg in the control group (=0.639). Mean diastolic BP decreased from 93.7 to 86.6 mm Hg in the intervention group and 93.9 to 86.3 mm Hg in the control group (=0.667). Hypertension control rates in the intervention and control groups were 20.8% and 15.8%, respectively (=0.318). Medication adherence was 84.2% in the intervention group and 86.2% in the control group (=0.705).
Financial incentives were effective in the short term for BP control, but a sustained effect of incentive-based BP control was not identified beyond 3 months of intervention. Future studies that focus on identifying the appropriate amount and structure of financial incentives for BP control are warranted.
URL: www.isrctn.org; Unique identifier: ISRCTN13467677.
高血压控制不佳是全球公共卫生面临的巨大挑战。基于行为和经济概念的激励方法可能会提高患者对治疗的依从性。
我们进行了一项 2 臂随机对照试验,以测试经济激励措施是否有助于中国血压控制不佳的高血压患者降低血压。参与者按照 1:1 的比例随机分为对照组和干预组。所有参与者都接受了基于微信的高血压管理标准教育和支持。干预组接受了经济激励措施,包括基于过程和结果的激励措施。
从基线到 12 个月随访,两组的血压降低和高血压控制率均无统计学差异。干预组收缩压从 158.7 降至 149.8mmHg,对照组从 159.7 降至 149.5mmHg(=0.639)。干预组舒张压从 93.7 降至 86.6mmHg,对照组从 93.9 降至 86.3mmHg(=0.667)。干预组和对照组的高血压控制率分别为 20.8%和 15.8%(=0.318)。干预组的药物依从性为 84.2%,对照组为 86.2%(=0.705)。
经济激励在短期内对血压控制有效,但在干预 3 个月后未发现基于激励的血压控制的持续效果。未来的研究需要关注确定适当的经济激励措施数量和结构以控制血压。