Nakao K, Isashiki M
Jpn J Ophthalmol. 1986;30(4):376-84.
Two Japanese young adults had an acute unilateral visual loss with no preceding general illness. Ophthalmoscopic examination revealed multiple, small discrete yellow-white lesions which appeared to be located at the level of the retinal pigment epithelium in the posterior fundus. There was also fine granularity of the fovea, and the optic disc margin was blurred. Fluorescein angiography demonstrated early hyperfluorescence of the lesions consisting of a cluster of punctate hyperfluorescent areas and late staining of the retinal pigment epithelium. These lesions regressed in a few weeks with return of the visual function to the normal level. The clinical picture of these cases is differentiated from acute inflammatory diseases primarily involving the retinal pigment epithelium and photoreceptors, and conforms to the multiple evanescent white dot syndrome that has recently been found in residents of the midwest region of the United States of America.
两名日本年轻人出现急性单侧视力丧失，之前无全身性疾病史。眼底镜检查发现多个小的、离散的黄白色病变，似乎位于后极部视网膜色素上皮层水平。黄斑也有细微颗粒状改变，视盘边缘模糊。荧光素血管造影显示病变早期出现由一群点状高荧光区组成的高荧光，以及视网膜色素上皮的晚期染色。这些病变在几周内消退，视力功能恢复到正常水平。这些病例的临床表现与主要累及视网膜色素上皮和光感受器的急性炎症性疾病不同，符合最近在美国中西部地区居民中发现的多发性一过性白点综合征。
