Matsumoto Yoko, Haen Sebastian P, Spaide Richard F
Vitreous-Retina-Macula Consultants of New York, New York, NY, USA.
Compr Ophthalmol Update. 2007 Jul-Aug;8(4):179-200; discussion 203-4.
The white dot syndromes are a heterogeneous group of rare inflammatory disorders affecting the retina, the retinal pigment epithelium, and the choroid. Not all of these diseases actually cause white dots, but they all have unique lesions in the fundus. We describe acute posterior multifocal placoid pigment epitheliopathy, serpiginous choroiditis, birdshot chorioretinopathy, multifocal choroiditis with panuveitis, diffuse subretinal fibrosis syndrome, punctate inner choroidopathy, multiple evanescent white dot syndrome, and diffuse unilateral subacute neuroretinitis as the white dot syndromes in this review. Some of these conditions share an association with systemic infectious diseases. In addition, treatment of these diseases is similar. Some can be treated with immunosuppressive therapy. Other treatment options include laser photocoagulation, topical or systemic steroid therapy, photodynamic therapy, and, most recently, anti-vascular endothelial growth factor agents. The new development in treatment may alter the visual prognosis of the patients, leading to a better outcome in visual acuity.
白点综合征是一组影响视网膜、视网膜色素上皮和脉络膜的罕见异质性炎症性疾病。并非所有这些疾病都会实际导致白点出现，但它们在眼底都有独特的病变。在本综述中，我们将急性后极部多灶性扁平状色素上皮病变、匐行性脉络膜炎、鸟枪弹样脉络膜视网膜病变、多灶性脉络膜炎伴全葡萄膜炎、弥漫性视网膜下纤维化综合征、点状内层脉络膜病变、多发性一过性白点综合征和弥漫性单侧亚急性神经视网膜炎描述为白点综合征。其中一些病症与全身性感染性疾病有关。此外，这些疾病的治疗方法相似。有些可以用免疫抑制疗法治疗。其他治疗选择包括激光光凝、局部或全身类固醇疗法、光动力疗法，以及最近的抗血管内皮生长因子药物。治疗方面的新进展可能会改变患者的视力预后，使视力获得更好的结果。
