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颈椎尤文肉瘤——一种罕见的疾病。

The Ewing's sarcoma of cervical spine-a rare occurrence.

机构信息

Department of Orthopedics, Hind Institute of Medical Sciences, Lucknow, India.

Department of Spine Surgery, Max Superspeciality Hospital, Ghaziabad, India.

出版信息

Spinal Cord Ser Cases. 2022 Jul 21;8(1):68. doi: 10.1038/s41394-022-00534-6.

DOI:10.1038/s41394-022-00534-6
PMID:35864101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9304365/
Abstract

INTRODUCTION

Ewing's sarcoma is a Primary Neuroectodermal Tumour (PNET) commonly affecting appendicular skeleton. The involvement of axial skeleton is very rare and that too of cervical spine is rarest. We present a case of Ewing's sarcoma involving cervical spine managed surgically, and its outcome.

CASE PRESENTATION

A 26-year-old male presented with 3-month history of neck pain and progressive motor weakness for 1 week. After clinical evaluation of sign and symptoms, MRI of cervical spine revealed a posterior neck mass over C2, C3 and C4. Because of mass effect and spinal cord compression, early surgical intervention was deemed necessary to stop progression of neurological deficit and make tissue diagnosis of lesion. On histopathological examination diagnosis of Ewing sarcoma was made. PET-CT showed C2 and C3 as primary site of involvement with no other site of involvement.

DISCUSSION

The Ewing's Sarcoma of the cervical spine is a rare occurrence and usually present in late and advanced stage. High index of suspicion should be present to make early diagnosis and prevent complications.

摘要

简介

尤文肉瘤是一种常见于四肢骨骼的原发性神经外胚层肿瘤(PNET)。发生于中轴骨骼的情况非常罕见,而发生于颈椎的情况则最为罕见。我们报告了一例累及颈椎的尤文肉瘤,该患者接受了手术治疗,并对其结果进行了分析。

病例介绍

一名 26 岁男性,因颈部疼痛 3 个月,且 1 周来逐渐出现运动无力而就诊。经过对症状和体征的临床评估,颈椎 MRI 显示 C2、C3 和 C4 水平有颈部后区肿块。由于肿块效应和脊髓压迫,为了阻止神经功能缺损的进展并对病变进行组织学诊断,早期手术干预被认为是必要的。组织病理学检查诊断为尤文肉瘤。PET-CT 显示 C2 和 C3 为受累的原发性部位,无其他部位受累。

讨论

颈椎尤文肉瘤是一种罕见的疾病,通常在晚期和进展期出现。为了尽早诊断和预防并发症,应该提高对此病的警惕性。

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本文引用的文献

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Multilevel Pedicular Osteotomies for En Bloc Resection of a Primary Ewing Sarcoma of the Subaxial Cervical Spine with Pedicle Screw Reconstruction.后路脊柱椎弓根螺钉固定下整块切除下颈椎原发性尤文肉瘤的多节段脊柱截骨术。
World Neurosurg. 2019 Dec;132:303-308. doi: 10.1016/j.wneu.2019.07.208. Epub 2019 Aug 5.
2
Ewing Sarcoma of the Spine: Prognostic Variables for Survival and Local Control in Surgically Treated Patients.脊柱尤文肉瘤:手术治疗患者的生存和局部控制的预后变量。
Spine (Phila Pa 1976). 2018 May 1;43(9):622-629. doi: 10.1097/BRS.0000000000002386.
3
A Unique Case of Primary Ewing's Sarcoma of the Cervical Spine in a 53-Year-Old Male: A Case Report and Review of the Literature.一名53岁男性颈椎原发性尤因肉瘤的独特病例:病例报告及文献综述
Case Rep Med. 2015;2015:402313. doi: 10.1155/2015/402313. Epub 2015 Feb 23.
4
Primary dumbbell-shaped Ewing's sarcoma of the cervical vertebra in adults: Four case reports and literature review.成人颈椎原发性哑铃形尤因肉瘤:4例报告及文献复习
Oncol Lett. 2012 Mar;3(3):721-725. doi: 10.3892/ol.2012.550. Epub 2012 Jan 3.
5
Extraskeletal Ewing's sarcoma: a report of 18 cases and literature review.骨外尤文肉瘤:18例报告及文献复习
Chin J Cancer. 2010 Apr;29(4):420-4. doi: 10.5732/cjc.009.10402.
6
Treatment of nonmetastatic Ewing's sarcoma family tumors of the spine and sacrum: the experience from a single institution.脊柱和骶骨非转移性尤因肉瘤家族性肿瘤的治疗:来自单一机构的经验。
Eur Spine J. 2009 Aug;18(8):1091-5. doi: 10.1007/s00586-009-0921-0. Epub 2009 Mar 11.
7
The Biology of Ewing sarcoma.尤因肉瘤的生物学
Cancer Lett. 2007 Aug 28;254(1):1-10. doi: 10.1016/j.canlet.2006.12.009. Epub 2007 Jan 23.
8
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Skeletal Radiol. 2004 Sep;33(9):506-13. doi: 10.1007/s00256-004-0810-x. Epub 2004 Jun 30.
9
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10
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