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腕关节周围正中神经、桡神经和尺神经阻滞联合关节内类固醇注射治疗上肢复杂性区域疼痛综合征的疗效:1 周随访研究。

Effectiveness of Peripheral Median, Radial, and Ulnar Nerve Block at Wrist along with Intra-Articular Steroid Injection in Shoulder Joint in Management of Complex Regional Pain Syndrome of Upper Limb: 1-Week Follow-Up Study.

机构信息

Department of Neurological Rehabilitation, NIMHANS, Bengaluru, Karnataka, India.

Centre for Community Medicine, AIIMS, New Delhi, India.

出版信息

Neurol India. 2022 May-Jun;70(3):1064-1068. doi: 10.4103/0028-3886.349618.

Abstract

BACKGROUND

Complex regional pain syndrome (CRPS) of upper limbs is one of the under-recognized painful disabling condition seen in many neurological conditions.

OBJECTIVE

To see the effectiveness of peripheral nerve blocks (PNB) along with intra-articular injection in shoulder joint in the improvement of pain, swelling and range of motion (ROM) of the upper limb in CRPS.

METHODS

It was a single-center, prospective study in male and female patients between 18 and 70 years with CRPS of the upper limb due to any etiology, within one year of illness. Single-dose of the intra-articular shoulder joint injection and peripheral nerve blocks at the wrist with steroid, 2% lignocaine, and sterile water was given. The primary outcome measure was a reduction in pain in the upper limb, assessed with a visual analog scale (VAS). Secondary outcome measures were an improvement in passive ROM of joints and a decrease in swelling of the hand. The significance of the P value was adjudged against an alpha of 0.05.

RESULTS

Thirty-three patients (25 men), with a mean (SD) age of 55.2 (9.4) years, and mean (SD) duration of illness of 101.9 (76.8) days were included. After 1 week, there was a significant improvement (P < 0.05) in the ROM of joints. The decrease in pain scores on VAS [mean difference -5.1 (CI -5.7, -4.5)] and reduction in hand swelling [mean difference -0.9 (CI -1.1, -0.7)] was also significant.

CONCLUSION

Peripheral median, radial, and ulnar nerve block at wrist along with intra-articular steroid injection in the shoulder joint is an effective method of management of CRPS of the upper limb.

摘要

背景

上肢复杂性区域疼痛综合征(CRPS)是许多神经疾病中常见的一种被低估的疼痛致残病症。

目的

观察肩部关节周围神经阻滞(PNB)联合关节内注射在改善 CRPS 上肢疼痛、肿胀和关节活动度(ROM)方面的效果。

方法

这是一项单中心、前瞻性研究,纳入了 18 至 70 岁的男女患者,均患有任何病因导致的上肢 CRPS,发病时间在 1 年内。单次关节内肩部注射和腕部周围神经阻滞,使用类固醇、2%利多卡因和无菌水。主要结局指标是上肢疼痛的减轻,采用视觉模拟评分(VAS)评估。次要结局指标是关节被动 ROM 的改善和手部肿胀的减轻。P 值的显著性判断标准为 0.05。

结果

共纳入 33 例患者(25 名男性),平均年龄(标准差)为 55.2(9.4)岁,平均(标准差)病程为 101.9(76.8)天。治疗 1 周后,ROM 明显改善(P<0.05)。VAS 评分的疼痛评分下降[平均差值-5.1(CI-5.7,-4.5)]和手部肿胀减少[平均差值-0.9(CI-1.1,-0.7)]也具有显著意义。

结论

腕部正中、桡侧和尺侧神经阻滞联合肩部关节内类固醇注射是治疗上肢 CRPS 的有效方法。

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