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关节内皮质类固醇注射与脉冲射频治疗肩部疼痛:一项前瞻性、随机、单盲研究。

Intra-articular corticosteroid injections versus pulsed radiofrequency in painful shoulder: a prospective, randomized, single-blinded study.

机构信息

Department of Anesthesiology, Pain Clinic, Faculty of Medicine, Ege University, Izmir, Turkey.

出版信息

Clin J Pain. 2010 Jun;26(5):386-92. doi: 10.1097/AJP.0b013e3181cf5981.

Abstract

OBJECTIVE

Chronic shoulder pain treatment is known to be a difficult and long process. The objective of this study is to compare the efficacy of intra-articular corticosteroid injection and pulse radiofrequency (PRF) applied to the suprascapular nerve in patients with shoulder pain.

METHODS

Fifty patients with shoulder pain were included in the study. Patients were randomly allocated into group 1 (intra-articular injection of corticosteroid) and group 2 (PRF to the suprascapular nerve). Outcome measures included a pain scale (visual analog scale; VAS), range of motion, Shoulder Pain and Disability Index (SPADI), the Short Form-36, Beck Depression Scale questionnaires, and paracetamol consumption.

RESULTS

In both groups, significant improvement was observed in all weeks in VAS, range of motion (active-passive), and SPADI subscores (P<0.05). Improvement was detected in most of the Short Form-36 scores at the end of the treatment in both groups (P<0.05), whereas no significant change was observed in Beck Depression Inventory score (P>0.05). When the groups were compared, a significant difference was found between the groups in favor of group 1 in terms of VAS at night in weeks 1, 4, and 12; VAS at rest in weeks 1 and 4; and VAS during movement in week 1 (P<0.05). There was also a significant difference in favor of group 1 observed in weeks 1, 4, and 12 in SPADI pain and total subscores (P<0.05). Paracetamol consumption was observed to be lower in group 1 (P<0.05).

CONCLUSIONS

Intra-articular injection of corticosteroid and PRF applied to the suprascapular nerve are effective in the treatment of painful shoulder. When 2 treatments are compared, it may be concluded that intra-articular steroid injection was more effective especially in the first weeks regarding pain than the PRF. Further studies are needed to confirm these results in the prospective treatment guidelines.

摘要

目的

慢性肩部疼痛的治疗过程较为复杂且漫长。本研究旨在比较关节内皮质类固醇注射和脉冲射频(PRF)应用于肩胛上神经治疗肩部疼痛的疗效。

方法

本研究纳入了 50 例肩部疼痛患者。患者被随机分配至 1 组(关节内皮质类固醇注射)和 2 组(肩胛上神经 PRF)。评估指标包括疼痛量表(视觉模拟评分;VAS)、活动范围、肩痛和残疾指数(SPADI)、简明健康调查问卷、贝克抑郁量表和扑热息痛的使用量。

结果

两组患者在 VAS、活动范围(主动-被动)和 SPADI 子评分方面,在所有周均观察到显著改善(P<0.05)。两组患者在治疗结束时大多数简明健康调查问卷评分均有所改善(P<0.05),而贝克抑郁量表评分无显著变化(P>0.05)。组间比较时,1 组在第 1、4 和 12 周的夜间 VAS、第 1 和 4 周的休息时 VAS 以及第 1 周的活动时 VAS 方面优于 2 组,差异具有统计学意义(P<0.05)。1 组在第 1、4 和 12 周的 SPADI 疼痛和总分子评分方面也优于 2 组,差异具有统计学意义(P<0.05)。1 组扑热息痛的使用量较低(P<0.05)。

结论

关节内皮质类固醇注射和 PRF 应用于肩胛上神经均可有效治疗肩部疼痛。当两种治疗方法进行比较时,可以得出结论,关节内注射皮质类固醇在治疗疼痛方面比 PRF 更有效,特别是在最初的几周。需要进一步的研究来确认这些结果在前瞻性治疗指南中的地位。

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