Meerson F Z, Ustinova E E
Kardiologiia. 1987 Mar;27(3):85-90.
Electrical cardiac fibrillation threshold was shown to be reduced twofold 2 months after the induction of experimental infarction in animals with postinfarction cardiosclerosis. Major contractility parameters at rest and under isometric load on the heart were also reduced essentially in these animals. Gradual postinfarction adaptation to high-altitude hypoxia in an altitude chamber resulted in a considerable (60%) increase in fibrillation threshold and virtually complete recovery of myocardial contractility, as well as a twofold reduction in scarred tissue mass. Possible use of adaptation to hypoxia for postinfarction rehabilitation on in man is discussed.
在患有心肌梗死后心脏硬化的动物中，实验性梗死诱发2个月后，心脏电颤动阈值降低了两倍。这些动物在静息状态和心脏等长负荷下的主要收缩参数也显著降低。在高原舱中，心肌梗死后逐渐适应高原缺氧，导致颤动阈值显著提高（60%），心肌收缩力几乎完全恢复，以及瘢痕组织质量减少两倍。文中讨论了将缺氧适应用于人类心肌梗死后康复的可能性。
