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[利用缺氧适应预防实验性梗死中心脏电稳定性紊乱]

[Prevention of disorders of the electric stability of the heart in experimental infarct using adaptation to hypoxia].

作者信息

Ustinova E E

出版信息

Biull Eksp Biol Med. 1988 Apr;105(4):401-3.

PMID:3359014
Abstract

It has been shown on rats preadapted to hypoxia in an altitude chamber that myocardial infarction induced by ligation of the coronary artery was accompanied by less disturbances in the electrical stability of the heart, namely by a twofold decrease in ventricular fibrillation threshold and a considerable decrease in the heart ectopic activity. Preliminary adaptation provided the maintenance of myocardial contractility in infarction.

摘要

在海拔舱中预先适应低氧环境的大鼠身上的研究表明，冠状动脉结扎诱发的心肌梗死伴随着心脏电稳定性的较小干扰，即室颤阈值降低两倍，心脏异位活动显著减少。预先适应可在梗死时维持心肌收缩力。

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