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维生素B12缺乏伴巨脾、溶血性贫血和全血细胞减少的不寻常表现:一例报告

An Unusual Presentation of Vitamin B12 Deficiency Associated With Massive Splenomegaly, Hemolytic Anemia, and Pancytopenia: A Case Report.

作者信息

Elhiday Hisham, Musa Muzamil, Hussaini Syed Ahmed, Al-Warqi Akram, Alfitori Gamal

机构信息

Internal Medicine, Hamad Medical Corporation, Doha, QAT.

Psychiatry, Hamad Medical Corporation, Doha, QAT.

出版信息

Cureus. 2022 Jun 18;14(6):e26058. doi: 10.7759/cureus.26058. eCollection 2022 Jun.

Abstract

Deficiency of vitamin B12 usually presents with symptoms of anaemia or neurological dysfunction. We report a case of a young lady who was found to be vitamin B12 deficient with massive splenomegaly, haemolytic anaemia, and pancytopenia. She was thoroughly investigated for other causes of similar presentation. Her symptoms and blood count drastically improved after two weeks of therapy with vitamin B12 supplementation. After reviewing the literature on unusual cases of vitamin B12 deficiency, our case is a very interesting read as it serves as a reminder for health care providers to be alert for these manifestations, which can be treated by simply replacing vitamin B12.

摘要

维生素B12缺乏通常表现为贫血或神经功能障碍症状。我们报告一例年轻女性病例,该患者被发现维生素B12缺乏,伴有巨大脾肿大、溶血性贫血和全血细胞减少。对其进行了全面检查以寻找类似表现的其他病因。补充维生素B12治疗两周后,她的症状和血细胞计数显著改善。在查阅了关于维生素B12缺乏异常病例的文献后,我们的病例很值得一读,因为它提醒医疗保健人员要警惕这些表现,而这些表现只需补充维生素B12即可治疗。

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