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侵袭性乳腺三阴性癌肉瘤的临床表现与治疗

Presentation and treatment of aggressive, Triple-Negative carcinosarcoma of the breast.

作者信息

Vizgan Niels, Jokar Tahereh Orouji, Enayati Ladan, Salyana Muhammad, Gotlieb Vladimir K

机构信息

Department of Chemistry Wesleyan University Middletown Connecticut USA.

St. Mary's General Hospital Passaic New Jersey USA.

出版信息

Clin Case Rep. 2022 Jul 18;10(7):e6020. doi: 10.1002/ccr3.6020. eCollection 2022 Jul.

Abstract

An extremely rare form of breast cancer, breast carcinosarcoma accounts for less than a percent of all breast malignancies and is highly aggressive. Composed of both cancerous epithelial and mesenchymal cell types, breast carcinosarcoma is associated with a poor prognosis compared to more common breast cancers, and typically lack the receptors typical of other breast carcinomas, which minimize potential targets for treatment. In this case report, we discuss a 56-year-old patient affected by carcinosarcoma of the breast at a T2N1 stage, and the decision-making process that factored into her treatment plan.

摘要

乳腺肉瘤样癌是一种极其罕见的乳腺癌形式,占所有乳腺恶性肿瘤的比例不到1%,且具有高度侵袭性。乳腺肉瘤样癌由癌性上皮细胞和间充质细胞类型组成,与更常见的乳腺癌相比,其预后较差,并且通常缺乏其他乳腺癌典型的受体,这使得潜在的治疗靶点减少。在本病例报告中,我们讨论了一名56岁处于T2N1期的乳腺肉瘤样癌患者,以及其治疗方案制定过程中的决策过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9770/9291258/0e296f864c66/CCR3-10-e6020-g001.jpg

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