Yoshida Chiaki, Yamamoto Hiroyuki, Inoue Tomohiro, Itoh Mitsuaki, Shimane Akira, Kawai Hiroya, Takaya Tomofumi
Division of Cardiovascular Medicine Hyogo Brain and Heart Center Himeji Japan.
Division of Cardiovascular Medicine Hyogo Prefectural Harima-Himeji General Medical Center Himeji Japan.
Clin Case Rep. 2022 Jul 19;10(7):e6104. doi: 10.1002/ccr3.6104. eCollection 2022 Jul.
Takotsubo cardiomyopathy (TCM) causes QT interval prolongation, potentially leading to a fatal arrhythmia. We report the first case of TCM associated with licorice-induced pseudoaldosteronism causing fatal arrhythmia in an older patient on polypharmacy including yokukansan (TJ-54) and galantamine. Polypharmacy should be resolved to prevent unexpected adverse events in older patients.
应激性心肌病(TCM)可导致QT间期延长,有可能引发致命性心律失常。我们报告首例与甘草诱发的假性醛固酮增多症相关的TCM病例,该病例在一名服用多种药物(包括逍遥散(TJ - 54)和加兰他敏)的老年患者中导致了致命性心律失常。应解决多重用药问题,以预防老年患者发生意外不良事件。