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甘草片致尖端扭转型室性心动过速

Torsade de Pointes Caused by a Compound Licorice Tablet.

机构信息

Department of Cardiology, Affiliated Hospital of Hebei University.

出版信息

Int Heart J. 2024 Jul 31;65(4):770-774. doi: 10.1536/ihj.23-609. Epub 2024 Jul 13.

Abstract

The clinical manifestations of licorice-induced pseudoaldosteronism include muscle weakness, periodic paralysis, hypokalemia, and hypertension. Excessive licorice consumption can lead to adverse reactions affecting multiple systems, including the endocrine, cardiovascular, nervous, digestive, and immune systems. Although licorice is a frequently used Chinese herbal medicine, life-threatening adverse reactions have been reported among its users. This article presents a case of severe hypokalemia, torsade de pointes, severe hypertension, and exacerbation of manic symptoms resulting from an overdose of compound licorice tablets. This study aimed to enhance the understanding of the causes of hypokalemia and raise awareness on the potentially fatal adverse reactions associated with licorice drugs.

摘要

甘草诱导的假性醛固酮增多症的临床表现包括肌肉无力、周期性瘫痪、低钾血症和高血压。过量食用甘草会导致影响多个系统的不良反应,包括内分泌、心血管、神经、消化和免疫系统。尽管甘草是一种常用的中草药,但已有报道称其使用者出现了危及生命的不良反应。本文介绍了一例因复方甘草片过量服用导致严重低钾血症、尖端扭转型室性心动过速、严重高血压和躁狂症状加重的病例。本研究旨在提高对低钾血症病因的认识,并提高对甘草类药物潜在致命不良反应的认识。

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