Elousrouti Layla Tahiri, Bentayeb Rafik, Douida Amal, Abid Hakima, Abraki Mohamed, Ibrahimi Adil, Elloudi Sara, Baybay Hanane, Elmernissi Fatimazahra, Lamrani Youssef Alaoui, Hammas Nawal, Elfatemi Hinde, Chbani Laila
Laboratoire d´Anatomie et de Cytologie Pathologiques, Centre Hospitalier Universitaire Hassan II de Fès, Fès, Maroc.
Laboratoire de Recherche Biomédicale et Translationnelle, Faculté de Médecine et de Pharmacie, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.
Pan Afr Med J. 2022 Apr 22;41:329. doi: 10.11604/pamj.2022.41.329.28965. eCollection 2022.
Adnexal carcinomas are rare, accounting for less than 1% of skin carcinomas. Sclerosus carcinoma of the sweat glands was first described by Goldstein et al. in 1982. We here report the case of a 33-year-old female patient with a retracted perianal skin lesion. Histological examination of perilesional skin biopsy, immunohistochemistry, and negative results of laboratory tests, radiological and endoscopic investigations allowed for the diagnosis of eccrine sclerosus carcinoma. This is a rare tumor, usually characterized by facial localization and slow but aggressive progression. It poses problems in differential diagnosis with benign and malignant tumors; hence the challenge encountered by pathologist of suspecting this carcinoma in patients with any sclerotic and infiltrating skin lesion characterized by slow progression, in a context of preservation of the general state and in the absence of neoplastic history as well as of feeling free to ask for new deep biopsies when in doubt.
附件癌很罕见，占皮肤癌的比例不到1%。汗腺硬化性癌于1982年由戈尔茨坦等人首次描述。我们在此报告一例33岁女性患者，其肛周皮肤病变回缩。对病变周围皮肤活检进行组织学检查、免疫组化检查，以及实验室检查、影像学和内镜检查的阴性结果，得以诊断为小汗腺硬化性癌。这是一种罕见的肿瘤，通常表现为面部定位，进展缓慢但具有侵袭性。它在与良性和恶性肿瘤的鉴别诊断中存在问题；因此，病理学家在面对任何以缓慢进展为特征的硬化性和浸润性皮肤病变患者时，在患者一般状况良好、无肿瘤病史且存疑时可自由要求进行新的深部活检的情况下，怀疑这种癌症会遇到挑战。
