Su Ying, Wang Zihao, Yu Yougui, Zheng Qing
School of Food and Chemical Engineering, Shaoyang University, Shaoyang, 422000, China.
Hunan Provincial Key Laboratory of New Technology and Application for Ecological Baijiu Production, Shaoyang University, Shaoyang, 422000, China.
Heliyon. 2022 Jul 12;8(7):e09940. doi: 10.1016/j.heliyon.2022.e09940. eCollection 2022 Jul.
Elucidating the pharmaceutical mechanisms behind traditional Chinese medicine (TCM) is the key to promote its modernization process. In China, soaking TCM in liquor has a history of thousands of years, and many TCMs have to be processed into liquor before they can be used to treat diseases. Chinese liquor (Baijiu) contains more than 2,000 trace components, the interaction mechanism between TCM and Baijiu still remains unclear, making TCM a "mystery". The TCM industry commonly employs chromatographic and spectrographic technology to investigate the redox activity of TCM substances. However, only investigating the redox differences in specific active substances cannot provide a complete understanding of the redox activity of TCM substances. Thus, we employed the electrochemical approach to study the overall redox activity of substances in TCM . The key result is that the redox substances in Baijiu function as a mediator for the redox reaction of extract. The redox efficiency of the extract is enhanced because of the faster electron transferability of the redox mediator in Baijiu.
阐明中药背后的药学机制是推动其现代化进程的关键。在中国，中药泡酒已有数千年历史，许多中药必须制成药酒才能用于治病。中国白酒含有2000多种微量成分，中药与白酒之间的相互作用机制仍不清楚，这使得中药成为一个“谜”。中药行业通常采用色谱和光谱技术来研究中药物质的氧化还原活性。然而，仅研究特定活性物质的氧化还原差异并不能全面了解中药物质的氧化还原活性。因此，我们采用电化学方法来研究中药中物质的整体氧化还原活性。关键结果是白酒中的氧化还原物质充当提取物氧化还原反应的介质。由于白酒中氧化还原介质的电子转移速度更快，提取物的氧化还原效率得以提高。
