Zhou Xiaobei, Chen Lei, Liu Hui-Xin
Health Sciences Institute, China Medical University, Shenyang, China.
Liaoning Key Laboratory of Obesity and Glucose/Lipid Associated Metabolic Diseases, China Medical University, Shenyang, China.
Front Nutr. 2022 Jul 5;9:933130. doi: 10.3389/fnut.2022.933130. eCollection 2022.
Research on obesity and related diseases has received attention from government policymakers; interventions targeting nutrient intake, dietary patterns, and physical activity are deployed globally. An urgent issue now is how can we improve the efficiency of obesity research or obesity interventions. Currently, machine learning (ML) methods have been widely applied in obesity-related studies to detect obesity disease biomarkers or discover intervention strategies to optimize weight loss results. In addition, an open source of these algorithms is necessary to check the reproducibility of the research results. Furthermore, appropriate applications of these algorithms could greatly improve the efficiency of similar studies by other researchers. Here, we proposed a mini-review of several open-source ML algorithms, platforms, or related databases that are of particular interest or can be applied in the field of obesity research. We focus our topic on nutrition, environment and social factor, genetics or genomics, and microbiome-adopting ML algorithms.
肥胖及相关疾病的研究已受到政府政策制定者的关注;针对营养摄入、饮食模式和身体活动的干预措施在全球范围内得到应用。当前的一个紧迫问题是如何提高肥胖研究或肥胖干预的效率。目前,机器学习(ML)方法已广泛应用于肥胖相关研究,以检测肥胖疾病生物标志物或发现优化减肥效果的干预策略。此外,这些算法的开源对于检验研究结果的可重复性很有必要。再者,这些算法的恰当应用能够极大提高其他研究人员开展类似研究的效率。在此,我们对几种特别有趣或可应用于肥胖研究领域的开源ML算法、平台或相关数据库进行了简要综述。我们将主题聚焦于采用ML算法的营养、环境与社会因素、遗传学或基因组学以及微生物组。