台湾植物药的抗肝毒性作用。

Antihepatotoxic actions of Formosan plant drugs.

作者信息

Yang L L, Yen K Y, Kiso Y, Hikino H

出版信息

J Ethnopharmacol. 1987 Jan-Feb;19(1):103-10. doi: 10.1016/0378-8741(87)90142-5.

Abstract

One hundred twenty-nine samples of Formosan plants were screened for antihepatotoxic activity in primary cultured hepatocytes to reveal that 19 and 26 plants exhibited more than 50% inhibition against cytotoxicity produced by carbon tetrachloride and D-galactosamine, respectively. Plants which disclosed significant antihepatotoxic activity in both assay methods are: Wedelia chinense, Mallotus repandus, Phyllantus urinaria, Loranthus parasiticus, Ludwigia octovalvis, Onychium japonicum, Tamarix chinensis and Ampelopsis brevipedunculata.

摘要

对129种台湾植物样本进行了原代培养肝细胞抗肝毒性活性筛选，结果显示，分别有19种和26种植物对四氯化碳和D - 半乳糖胺产生的细胞毒性表现出超过50%的抑制作用。在两种检测方法中均显示出显著抗肝毒性活性的植物有：蟛蜞菊、白背叶、叶下珠、桑寄生、丁香蓼、日本金粉蕨、柽柳和短柄蛇葡萄。