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非法药物使用与内镜检查:我们何时说“不”?

Illicit Drug Use and Endoscopy: When Do We Say No?

机构信息

Department of Internal Medicine, University of Nebraska Medical Center, 982000 Medical Center Drive, Omaha, NE, 68198, USA.

Division of Gastroenterology & Hepatology, University of Nebraska Medical Center, 982000 Medical Center Drive, Omaha, NE, 68198, USA.

出版信息

Dig Dis Sci. 2022 Dec;67(12):5371-5381. doi: 10.1007/s10620-022-07619-0. Epub 2022 Jul 22.

Abstract

BACKGROUND

Illicit drug use (IDU) is often encountered in patients undergoing elective ambulatory surgical procedures such as endoscopy. Given the variety of systemic effects of these drugs, sedation and anesthetics are believed to increase the risk of cardiopulmonary complications during procedures. Procedural cancelations are common, regardless of the drug type, recency of use, and total dosage consumed. There is a lack of institutional and society recommendations regarding the optimal approach to performing outpatient endoscopy on patients with IDU.

AIM

To review the literature for current recommendations regarding the optimal management of outpatient elective endoscopic procedures in patients with IDU. Secondary aim is to provide guidance for clinicians who encounter IDU in endoscopic practice.

METHODS

Systematic review of PubMed, CINAHL, Embase, and Google Scholar for articles presenting data on outcomes of elective procedures in patients using illicit drugs.

RESULTS

There are no clinically relevant differences in periprocedural complications or mortality in cannabis users compared to non-users. Endoscopy in patients with remote cocaine use was also found to have similar outcomes to recent use.

CONCLUSIONS

Canceling endoscopic procedures in patients with recent IDU without consideration of the type of drug, dosage, and chronicity may lead to unnecessary delays in care and increased patient morbidity. Healthcare systems would benefit from additional guidelines for evaluating the patient with recent illicit drug use for acute intoxication and consider proceeding with procedures in the non-toxic population.

摘要

背景

在接受择期门诊手术(如内镜检查)的患者中,常发现有非法药物使用(IDU)。鉴于这些药物的全身作用多种多样,镇静剂和麻醉剂被认为会增加手术过程中心肺并发症的风险。无论药物类型、使用时间长短和总剂量如何,手术取消都很常见。对于 IDU 患者进行门诊内镜检查的最佳方法,机构和社会都缺乏建议。

目的

回顾文献,了解目前关于 IDU 患者择期门诊内镜手术最佳管理的建议。次要目的是为在内镜实践中遇到 IDU 的临床医生提供指导。

方法

对 PubMed、CINAHL、Embase 和 Google Scholar 进行系统评价,以获取有关使用非法药物的患者进行择期手术的结局的文章数据。

结果

与非使用者相比,大麻使用者在围手术期并发症或死亡率方面没有明显差异。对近期使用可卡因的患者进行内镜检查也发现与近期使用的结果相似。

结论

如果不考虑药物类型、剂量和持续时间而取消近期 IDU 患者的内镜检查可能会导致不必要的护理延迟和增加患者的发病率。医疗保健系统将受益于更多的指南,以评估最近使用非法药物的患者是否有急性中毒,并考虑在非中毒人群中进行手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a49/9306238/f156736b6c7c/10620_2022_7619_Fig1_HTML.jpg

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