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HPM-Net:用于 CT 图像中肝脏血管分割的分层渐进多尺度网络。

HPM-Net: Hierarchical progressive multiscale network for liver vessel segmentation in CT images.

机构信息

School of Computer Science and Communication Engineering, Jiangsu University, Zhenjiang 212013, China.

School of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, China.

出版信息

Comput Methods Programs Biomed. 2022 Sep;224:107003. doi: 10.1016/j.cmpb.2022.107003. Epub 2022 Jul 7.

Abstract

BACKGROUND AND OBJECTIVE

The segmentation and visualization of liver vessels in 3D CT images are essential for computer-aided diagnosis and preoperative planning of liver diseases. Due to the irregular structure of liver vessels and image noise, accurate extraction of liver vessels is difficult. In particular, accurate segmentation of small vessels is always a challenge, as multiple single down-sampling usually results in a loss of information.

METHODS

In this paper, we propose a hierarchical progressive multiscale learning network (HPM-Net) framework for liver vessel segmentation. Firstly, the hierarchical progressive multiscale learning network combines internal and external progressive learning methods to learn semantic information about liver vessels at different scales by acquiring receptive fields of different sizes. Secondly, to better capture vessel features, we propose a dual-branch progressive 3D Unet, which uses a dual-branch progressive (DBP) down-sampling strategy to reduce the loss of detailed information in the process of network down-sampling. Finally, a deep supervision mechanism is introduced into the framework and backbone network to speed up the network convergence and achieve better training of the network.

RESULTS

We conducted experiments on the public dataset 3Dircadb for liver vessel segmentation. The average dice coefficient and sensitivity of the proposed method reached 75.18% and 78.84%, respectively, both higher than the original network.

CONCLUSION

Experimental results show that the proposed hierarchical progressive multiscale network can accurately segment the labeled liver vessels from the CT images.

摘要

背景与目的

在 3D CT 图像中对肝血管进行分割和可视化对于计算机辅助诊断和肝脏疾病的术前规划至关重要。由于肝血管的不规则结构和图像噪声,准确提取肝血管较为困难。特别是,小血管的准确分割一直是一个挑战,因为多次单一的下采样通常会导致信息丢失。

方法

在本文中,我们提出了一种用于肝血管分割的分层渐进多尺度学习网络(HPM-Net)框架。首先,分层渐进多尺度学习网络结合了内部和外部渐进学习方法,通过获取不同大小的感受野来学习不同尺度下肝血管的语义信息。其次,为了更好地捕捉血管特征,我们提出了一种双分支渐进 3D U-Net,它使用双分支渐进(DBP)下采样策略来减少网络下采样过程中详细信息的丢失。最后,将深度监督机制引入到框架和骨干网络中,以加快网络收敛速度,实现网络更好的训练。

结果

我们在公共数据集 3Dircadb 上进行了肝血管分割实验。与原始网络相比,该方法的平均骰子系数和敏感度分别达到 75.18%和 78.84%。

结论

实验结果表明,所提出的分层渐进多尺度网络可以准确地从 CT 图像中分割出有标签的肝血管。

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