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聚焦超声、免疫疗法与化疗的联合应用:乳腺癌治疗的新视角

Combination of Focused Ultrasound, Immunotherapy, and Chemotherapy: New Perspectives in Breast Cancer Therapy.

作者信息

Dahan Myléva, Cortet Marion, Lafon Cyril, Padilla Frédéric

机构信息

LabTAU, INSERM, Centre Léon Bérard, Université Lyon 1, Univ Lyon, Lyon, France.

Service de Gynécologie Obstétrique, Hôpital de la Croix Rousse, Hospices Civils de Lyon, Lyon, France.

出版信息

J Ultrasound Med. 2023 Feb;42(3):559-573. doi: 10.1002/jum.16053. Epub 2022 Jul 23.

DOI:10.1002/jum.16053
PMID:35869903
Abstract

Focused ultrasound is a treatment modality increasingly used for diverse therapeutic applications, and currently approved for several indications, including prostate cancers and uterine fibroids. But what about breast cancer? Breast cancer is the most common and deadliest cancer in women worldwide. While there are different treatment strategies available, there is a need for development of more effective and personalized modalities, with fewer side effects. Therapeutic ultrasound is such an option, and this review summarizes the state of the art in their use for the treatment of breast cancer and evaluate potentials of novel treatment approaches combining therapeutic ultrasound, immuno- and chemo-therapies.

摘要

聚焦超声是一种越来越多地用于各种治疗应用的治疗方式,目前已被批准用于多种适应症,包括前列腺癌和子宫肌瘤。但乳腺癌呢?乳腺癌是全球女性中最常见、最致命的癌症。虽然有不同的治疗策略,但仍需要开发更有效、更个性化且副作用更少的治疗方式。治疗性超声就是这样一种选择,本综述总结了其用于治疗乳腺癌的最新技术水平,并评估了将治疗性超声与免疫疗法和化学疗法相结合的新型治疗方法的潜力。

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