MGM Institute of Biosciences and Technology, Mahatma Gandhi Mission University N-6, CIDCO, Aurangabad-431003, Maharashtra, India.
Novo Nordisk Centre for Biosustainability, Technical University of Denmark, B220 Kemitorvet, 2800 Kgs, Lyngby, Denmark.
Comp Biochem Physiol Part D Genomics Proteomics. 2022 Sep;43:101015. doi: 10.1016/j.cbd.2022.101015. Epub 2022 Jul 14.
Since proteins play an important role in the life of an organism, many researchers are now looking at how genes and proteins interact to form different proteins. It is anticipated that the creation of adequate tools for rapid analysis of proteins will accelerate the determination of functional aspects of these biomolecules and develop new biomarkers and therapeutic targets for the diagnosis and treatment of various diseases. Though shrimp contains high-quality marine proteins, there are reports about the heavy losses to the shrimp industry due to the poor quality of shrimp production and many times due to mass mortality also. Frequent outbreaks of diseases, water pollution, and quality of feed are some of the most recognized reasons for such losses. In the seafood export market, shrimp occupies the top position in currency earnings and strengthens the economy of many developing nations. Therefore, it is vital for shrimp-producing companies they produce healthy shrimp with high-quality protein. Though aquaculture is a very competitive market, global awareness regarding the use of scientific knowledge and emerging technologies to obtain better-farmed organisms through sustainable production has enhanced the importance of proteomics in seafood biology research. Proteomics, as a powerful tool, has therefore been increasingly used to address several issues in shrimp aquaculture. In the present paper, efforts have been made to address some of them, particularly the role of proteomics in reproduction, breeding and spawning, immunological responses and disease resistance capacity, nutrition and health, microbiome and probiotics, quality and safety of shrimp production, bioinformatics applications in proteomics, the discovery of protein biomarkers, and mitigating biotic and abiotic stresses. Future challenges and research directions on proteomics in shrimp aquaculture have also been discussed.
由于蛋白质在生物体的生命活动中起着重要的作用,现在许多研究人员都在研究基因和蛋白质如何相互作用形成不同的蛋白质。预计创建足够的工具来快速分析蛋白质将加速确定这些生物分子的功能方面,并开发新的生物标志物和治疗靶点,用于诊断和治疗各种疾病。尽管虾含有高质量的海洋蛋白质,但由于虾类生产质量差和多次大规模死亡,虾类产业遭受了严重损失。疾病频繁爆发、水污染和饲料质量是造成这种损失的一些最公认的原因。在海鲜出口市场中,虾类在货币收入中占据首位,加强了许多发展中国家的经济。因此,对于虾类生产企业来说,生产健康的、高质量蛋白质的虾类至关重要。尽管水产养殖是一个竞争非常激烈的市场,但全球对利用科学知识和新兴技术通过可持续生产获得更好养殖生物的认识不断提高,这使得蛋白质组学在海鲜生物学研究中的重要性日益增强。蛋白质组学作为一种强大的工具,因此越来越多地被用于解决虾类水产养殖中的几个问题。在本文中,我们努力解决了其中的一些问题,特别是蛋白质组学在繁殖、育种和产卵、免疫反应和疾病抵抗力、营养和健康、微生物组和益生菌、虾类生产的质量和安全、蛋白质组学生物信息学应用、蛋白质生物标志物的发现以及减轻生物和非生物胁迫方面的作用。还讨论了虾类水产养殖中蛋白质组学的未来挑战和研究方向。