Centro de Ciências do Mar do Algarve (CCMar), Universidade do Algarve, Campus de Gambelas, 8005-139 Faro, Portugal.
J Proteomics. 2012 Jul 19;75(14):4325-45. doi: 10.1016/j.jprot.2012.03.042. Epub 2012 Apr 4.
Over the last forty years global aquaculture presented a growth rate of 6.9% per annum with an amazing production of 52.5 million tonnes in 2008, and a contribution of 43% of aquatic animal food for human consumption. In order to meet the world's health requirements of fish protein, a continuous growth in production is still expected for decades to come. Aquaculture is, though, a very competitive market, and a global awareness regarding the use of scientific knowledge and emerging technologies to obtain a better farmed organism through a sustainable production has enhanced the importance of proteomics in seafood biology research. Proteomics, as a powerful comparative tool, has therefore been increasingly used over the last decade to address different questions in aquaculture, regarding welfare, nutrition, health, quality, and safety. In this paper we will give an overview of these biological questions and the role of proteomics in their investigation, outlining the advantages, disadvantages and future challenges. A brief description of the proteomics technical approaches will be presented. Special focus will be on the latest trends related to the aquaculture production of fish with defined nutritional, health or quality properties for functional foods and the integration of proteomics techniques in addressing this challenging issue.
在过去的四十年中，全球水产养殖业以每年 6.9%的速度增长，令人惊叹的是，2008 年的产量达到了 5250 万吨，占人类食用水生动物食品的 43%。为了满足世界对鱼类蛋白的健康需求，预计未来几十年水产养殖业仍将持续增长。然而，水产养殖业是一个极具竞争力的市场，人们越来越意识到需要利用科学知识和新兴技术，通过可持续生产获得更好的养殖生物，这使得蛋白质组学在海鲜生物学研究中的重要性日益增强。作为一种强大的比较工具，蛋白质组学在过去十年中越来越多地被用于解决水产养殖中的不同问题，包括福利、营养、健康、质量和安全。本文将概述这些生物学问题以及蛋白质组学在其研究中的作用，阐述其优缺点和未来的挑战。本文还将简要介绍蛋白质组学技术方法。特别关注与具有特定营养、健康或质量特性的功能性食品的鱼类养殖生产相关的最新趋势，以及蛋白质组学技术在解决这一具有挑战性问题方面的应用。
