在携带艾氏腹水癌细胞的动物中诱导2',5'-寡聚腺苷酸合成酶。
Induction of 2',5'oligo (A) synthetase in animals bearing Ehrlich ascites tumor cells.
作者信息
Galaktidou G, Kortsaris A, Papageorgiou A, Koliais S I
出版信息
Microbiologica. 1987 Apr;10(2):143-50.
PMID:3587063
Abstract
The activity of 2',5'oligo(A) synthetase in experimental mice inoculated with poly(I) poly(C) is higher in the animals with transplantable tumors (Ehrlich Ascites Tumor cells) compared to animals without the tumor. The higher enzymatic activity is detected in tissue homogenates from liver and spleen, as well as in homogenates from the Ascites cells.
摘要
接种聚肌苷酸-聚胞苷酸（poly(I) poly(C)）的实验小鼠中，与无肿瘤动物相比，携带可移植肿瘤（艾氏腹水瘤细胞）的动物体内2',5'-寡聚腺苷酸合成酶的活性更高。在肝脏和脾脏的组织匀浆以及腹水细胞匀浆中均检测到较高的酶活性。
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