University of Illinois at Urbana-Champaign, USA.
Johns Hopkins University, USA.
Health Place. 2022 Jul;76:102858. doi: 10.1016/j.healthplace.2022.102858. Epub 2022 Jul 21.
Limited studies examine how prenatal environmental and social exposures jointly impact perinatal health. Here we investigated relationships between a neighborhood-level combined exposure (CE) index assessed during pregnancy and perinatal outcomes, including birthweight, gestational age, and preterm birth. Across all participants, higher CE index scores were associated with small decreases in birthweight and gestational age. We also observed effect modification by race; infants born to Black pregnant people had a greater risk of preterm birth for higher CE values compared to White infants. Overall, our results suggest that neighborhood social and environmental exposures have a small but measurable joint effect on neonatal indicators of health.
有限的研究探讨了产前环境和社会暴露如何共同影响围产期健康。在这里，我们调查了在怀孕期间评估的邻里层面综合暴露 (CE) 指数与围产儿结局（包括出生体重、胎龄和早产）之间的关系。在所有参与者中，较高的 CE 指数得分与出生体重和胎龄的轻微下降有关。我们还观察到种族的效应修饰作用；与白人婴儿相比，黑人孕妇的婴儿在较高的 CE 值下，早产的风险更高。总的来说，我们的研究结果表明，邻里社会和环境暴露对新生儿健康指标有一定的、可衡量的共同影响。
