Yaprak Bayrak Busra, Sen Harun Emre, Eruyar Ahmet Tugrul, Etus Volkan
Department of Pathology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.
Department of Neurosurgery, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.
Neuropathology. 2023 Feb;43(1):95-99. doi: 10.1111/neup.12851. Epub 2022 Jul 24.
Cranial fasciitis (CF) is a rare, rapidly growing, benign fibroproliferative lesion of the skull in the pediatric population. It is characterized by benign mesenchymal proliferation of spindle cells arranged as short, intersecting loose fascicles within a fibromyxoid stroma, and mostly appears as a single mass. A surgical excision with clear surgical margins is definitively curative for CF. Up to date only two cases with multiple CF have been reported in the literature. In this report, we describe a 1-year-old girl with multiple locations of CF, as the first case to be reported in the Turkish population. The radiological and morphological findings of our case were comparable with the observations of the two previous reports in the literature. Histopathological examination remains to be the gold-standard for differential diagnosis of CF, as the treatment of this lesion differs from other malignancies of the skull in the pediatric population.
颅骨筋膜炎（CF）是儿科人群中一种罕见的、生长迅速的颅骨良性纤维增生性病变。其特征是梭形细胞的良性间叶增生，这些细胞排列成短的、相互交叉的疏松束状，位于纤维黏液样基质中，且大多表现为单个肿块。手术切除且手术切缘清晰对CF具有明确的治愈效果。迄今为止，文献中仅报道了两例多发CF病例。在本报告中，我们描述了一名患有多处CF的1岁女孩，这是土耳其人群中报道的首例。我们病例的影像学和形态学表现与文献中之前的两份报告的观察结果相当。组织病理学检查仍是CF鉴别诊断的金标准，因为该病变的治疗与儿科人群中颅骨的其他恶性肿瘤不同。
