Hand Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, China.
Department of Orthopaedics, Changzhi Second People's Hospital, Changzhi, Shanxi 046000, China.
Comput Math Methods Med. 2022 Jul 15;2022:9052770. doi: 10.1155/2022/9052770. eCollection 2022.
To investigate the effect of annular external fixator-assisted bone transport in the treatment of traumatic massive bone defect of tibia on clinical healing, pain stress, and joint function.
From January 2018 to November 2021, 146 patients with traumatic massive bone defect of tibia were selected as the research objects, and they were divided into observation group (annular external fixator-assisted bone transport, 71 cases) and control group (unilateral external fixator bone lengthening, 75 cases) according to different surgical methods. The therapeutic efficacy, fracture healing-related indexes, and postoperative range of motion of the knee joint were compared between the two groups. Callus healing was evaluated by Fernandez-Esteve callus score, and joint function was evaluated by Paley score, American Knee society score (AKSS), and Baird-Jackson ankle score. The changes of pain mediator (serum substance P (SP), neuropeptide Y (NPY), prostaglandin E2 (PGE2), and tumor necrosis factor- (TNF-)) and stress indexes (adrenocorticotropic hormone (ACTH), cortisol (COR), and nor Epinephrine (NE)) were observed before and after treatment in two groups. The incidence of postoperative complications was analyzed.
There were no significant differences in total effective rate and bone lengthening between the two groups ( > 0.05). The bone healing time and callus formation time in the observation group were shorter than those in the control group, and the Fernandez-Esteve callus score was higher than that in the control group ( < 0.05). The levels of SP, NPY, PGE2, TNF-, ACTH, COR, and NE in the observation group were lower than those in the control group ( < 0.05). AKSS and Baird-Jackson scores in the observation group after operation were higher than those in the control group ( < 0.05). There was no significant difference in the incidence of postoperative complications between the two groups ( > 0.05).
Annular external fixator-assisted bone transport can promote postoperative fracture healing, reduce pain stress level, and improve joint function of patients with traumatic massive bone defect of tibia.
探讨环形外固定架辅助骨搬运治疗胫骨创伤性大段骨缺损的临床疗效、疼痛应激及关节功能。
选取 2018 年 1 月至 2021 年 11 月胫骨创伤性大段骨缺损患者 146 例,按手术方法不同分为观察组(环形外固定架辅助骨搬运,71 例)和对照组(单侧外固定架骨延长,75 例)。比较两组患者的治疗效果、骨折愈合相关指标、膝关节术后活动度。采用 Fernandez-Esteve 骨痂评分评估骨痂愈合情况,采用 Paley 评分、美国膝关节协会评分(AKSS)、Baird-Jackson 踝关节评分评估关节功能。观察两组患者治疗前后疼痛介质(血清 P 物质(SP)、神经肽 Y(NPY)、前列腺素 E2(PGE2)、肿瘤坏死因子-(TNF-))和应激指标(促肾上腺皮质激素(ACTH)、皮质醇(COR)、去甲肾上腺素(NE))的变化,分析术后并发症发生情况。
两组总有效率和骨延长率比较,差异无统计学意义( > 0.05)。观察组骨愈合时间、骨痂形成时间短于对照组,Fernandez-Esteve 骨痂评分高于对照组( < 0.05)。观察组 SP、NPY、PGE2、TNF-、ACTH、COR、NE 水平低于对照组( < 0.05)。观察组术后 AKSS、Baird-Jackson 评分高于对照组( < 0.05)。两组术后并发症发生率比较,差异无统计学意义( > 0.05)。
环形外固定架辅助骨搬运可促进胫骨创伤性大段骨缺损患者术后骨折愈合,降低疼痛应激水平,改善关节功能。