Setiawaty Vivi, Puspandari Nelly, Saraswati Ratih Dian, Febriyana Dwi, Febrianti Tati, Rukminiati Yuni, Muna Fauzul, Fitriana Fitriana, Safari Dodi, Pratama Rahadian, Lienggonegoro Lisa Andriani, Sunarno Sunarno
National Referal Infectious Diseases Hospital Prof. Dr. Sulianti Saroso, Jakarta, Indonesia.
Centre for Research and Development of Biomedical and Basic Health Technology, National Institute of Health Research and Development (NIHRD), Ministry of Health, Jakarta, Indonesia.
Data Brief. 2022 Jul 14;43:108460. doi: 10.1016/j.dib.2022.108460. eCollection 2022 Aug.
() is the causative agent of diphtheria. The main virulence factor of is diphtheria toxin, which is encoded by the gene and regulated by the gene. The and genes are used as genetic markers to identify bacteria causing diphtheria by PCR. Here, we present the whole-genome sequencing (WGS) data of 18 isolates from diphtheria outbreaks in different regions in Indonesia. We used these data to identify (SNPs) associated with the and genes to verify the accuracy of the PCR assay and performed molecular typing with a multilocus sequence typing (MLST) approach. The data can be used for further analyses, such as antimicrobial resistance and bacterial virulence factors.
（）是白喉的病原体。其主要毒力因子是白喉毒素，由基因编码并受基因调控。基因和基因用作通过聚合酶链反应（PCR）鉴定引起白喉的细菌的遗传标记。在此，我们展示了来自印度尼西亚不同地区白喉暴发的18株分离株的全基因组测序（WGS）数据。我们利用这些数据鉴定与基因和基因相关的单核苷酸多态性（SNP），以验证PCR检测的准确性，并采用多位点序列分型（MLST）方法进行分子分型。这些数据可用于进一步分析，如抗菌药物耐药性和细菌毒力因子。
