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EB病毒和巨细胞病毒IgM均呈阳性:一个临床难题。

IgM Positivity for Both EBV and CMV: A Clinical Conundrum.

作者信息

Jhaveri Tulip A, Harris Courtney, Sax Paul E

机构信息

Division of Infectious Diseases, University of Mississippi Medical Center, Jackson, Mississippi, USA.

Division of Infectious Diseases, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Open Forum Infect Dis. 2022 Jun 24;9(7):ofac316. doi: 10.1093/ofid/ofac316. eCollection 2022 Jul.

DOI:10.1093/ofid/ofac316
PMID:35873288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9297312/
Abstract

A review of 28 patients who tested positive for both Epstein-Barr virus and cytomegalovirus immunoglobulin M at an academic medical center revealed that dual positivity is more common than previously reported. These cases require careful review of the history and sometimes supplemental testing. This report highlights features of patients with dual positivity and provides recommendations on interpretation of the results.

摘要

对某学术医学中心28例同时检测出爱泼斯坦-巴尔病毒和巨细胞病毒免疫球蛋白M呈阳性的患者进行的一项回顾显示,双重阳性比之前报道的更为常见。这些病例需要仔细回顾病史,有时还需要进行补充检测。本报告重点介绍了双重阳性患者的特征,并就结果解读提供了建议。

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本文引用的文献

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J Infect Chemother. 2019 Jun;25(6):431-436. doi: 10.1016/j.jiac.2019.01.012. Epub 2019 Feb 15.
2
EBV VCA IgM and cytomegalovirus IgM dual positivity is a false positive finding related to age and hepatic involvement of primary Epstein-Barr virus infection in children.EBV VCA IgM和巨细胞病毒IgM双阳性是与儿童原发性EB病毒感染的年龄及肝脏受累相关的假阳性结果。
Medicine (Baltimore). 2018 Sep;97(38):e12380. doi: 10.1097/MD.0000000000012380.
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Clinical and laboratory differences between Epstein-Barr and cytomegalovirus infectious mononucleosis in children.儿童传染性单核细胞增多症中EB病毒与巨细胞病毒感染的临床及实验室差异
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Age-specific prevalence of Epstein-Barr virus infection among individuals aged 6-19 years in the United States and factors affecting its acquisition.美国 6-19 岁人群中 Epstein-Barr 病毒感染的年龄特异性流行率及其影响获得感染的因素。
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