Guo Yuan, Liu Yi, Guan Mingdong, Tang Hongchi, Wang Zilong, Lin Lihua, Pang Hao
National Engineering Research Center for Non-Food Biorefinery, State Key Laboratory of Non-Food Biomass and Enzyme Technology, Guangxi Key Laboratory of Bio-refinery, Guangxi Academy of Sciences 98 Daling Road Nanning 530007 China
College of Life Science and Technology, Guangxi University Nanning 530004 China
RSC Adv. 2022 Jun 29;12(29):18848-18863. doi: 10.1039/d1ra09396g. eCollection 2022 Jun 22.
Due to energy and environmental concerns, biobutanol is gaining increasing attention as an alternative renewable fuel owing to its desirable fuel properties. Biobutanol production from lignocellulosic biomass through acetone-butanol-ethanol (ABE) fermentation has gained much interest globally due to its sustainable supply and non-competitiveness with food, but large-scale fermentative production suffers from low product titres and poor selectivity. This review presents recent developments in lignocellulosic butanol production, including pretreatment and hydrolysis of hemicellulose and cellulose during ABE fermentation. Challenges are discussed, including low concentrations of fermentation sugars, inhibitors, detoxification, and carbon catabolite repression. Some key process improvements are also summarised to guide further research and development towards more profitable and commercially viable butanol fermentation.
由于能源和环境问题，生物丁醇因其理想的燃料特性作为一种替代性可再生燃料正受到越来越多的关注。通过丙酮-丁醇-乙醇（ABE）发酵从木质纤维素生物质生产生物丁醇因其可持续供应且不与食品竞争而在全球引起了广泛关注，但大规模发酵生产存在产品滴度低和选择性差的问题。本文综述了木质纤维素丁醇生产的最新进展，包括ABE发酵过程中半纤维素和纤维素的预处理及水解。讨论了面临的挑战，包括发酵糖浓度低、抑制剂、解毒和碳分解代谢物阻遏。还总结了一些关键的工艺改进措施，以指导进一步的研究和开发，实现更具盈利性和商业可行性的丁醇发酵。
