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解析宏基因组学方法在微生物生物燃料生产中的应用。

Unravelling Metagenomics Approach for Microbial Biofuel Production.

机构信息

Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India.

Biochemical Process Engineering, Division of Chemical Engineering, Department of Civil, Environmental, and Natural Resources Engineering, Luleå University of Technology, SE-971 87 Luleå, Sweden.

出版信息

Genes (Basel). 2022 Oct 25;13(11):1942. doi: 10.3390/genes13111942.

Abstract

Renewable biofuels, such as biodiesel, bioethanol, and biobutanol, serve as long-term solutions to fossil fuel depletion. A sustainable approach feedstock for their production is plant biomass, which is degraded to sugars with the aid of microbes-derived enzymes, followed by microbial conversion of those sugars to biofuels. Considering their global demand, additional efforts have been made for their large-scale production, which is ultimately leading breakthrough research in biomass energy. Metagenomics is a powerful tool allowing for functional gene analysis and new enzyme discovery. Thus, the present article summarizes the revolutionary advances of metagenomics in the biofuel industry and enlightens the importance of unexplored habitats for novel gene or enzyme mining. Moreover, it also accentuates metagenomics potentials to explore uncultivable microbiomes as well as enzymes associated with them.

摘要

可再生生物燃料,如生物柴油、生物乙醇和生物丁醇,是解决化石燃料枯竭的长期方案。它们的生产可持续性原料是植物生物质,在微生物衍生酶的帮助下将其降解为糖,然后通过微生物将这些糖转化为生物燃料。考虑到它们的全球需求,已经做出了更多努力来大规模生产生物燃料,这最终推动了生物质能源领域的突破性研究。宏基因组学是一种强大的工具,可以进行功能基因分析和新酶的发现。因此,本文总结了宏基因组学在生物燃料工业中的革命性进展,并说明了探索未知生境对挖掘新基因或新酶的重要性。此外,它还强调了宏基因组学在探索不可培养微生物组及其相关酶方面的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38c6/9689425/bdc1a17bfed1/genes-13-01942-g001.jpg

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