Jackson D G, Lim D J
Acta Otolaryngol. 1978 Jul-Aug;86(1-2):71-88. doi: 10.3109/00016487809124722.
The fine morphology of the advancing front of the cholesteatoma and the mucocutaneous juction of implanted skin in the feline bulla have been investigated. Inflammatory cell infiltration was frequently observed at the advancing front and the mucocutaneous junction. It is suggested that this frequent inflammation at this junction is due to the lack of a tight seal. In the advancing front, epidermal migrating cells appear to be lower spinous cells (or "suprabasalar" cells) rather than basal cells. It appears that the slender cell processes of the migrating cells make the initial attachment to the fibrin and/or basement membrane left behind by the degenerated epithelial cells as a result of inflammation and migrate along these structures, using them as a guide. Implanted skin in the cat's bulla failed to develop a pearl formation but frequently developed an epiboly, in which case the epidermis receded and was partly replaced by mucous membrane, and its stroma was heavily invaded by mucous epithelium, resembling tubular glands.
对猫中耳胆脂瘤进展前沿及植入皮肤的黏膜皮肤交界处的精细形态进行了研究。在进展前沿和黏膜皮肤交界处经常观察到炎性细胞浸润。提示该交界处频繁出现炎症是由于缺乏紧密密封。在进展前沿，表皮迁移细胞似乎是棘层下部细胞（或“基底层上”细胞）而非基底细胞。似乎迁移细胞细长的细胞突起最初附着于因炎症而退变的上皮细胞留下的纤维蛋白和/或基底膜，并沿着这些结构迁移，将其作为引导。猫中耳植入的皮肤未形成珍珠样结构，但常形成外包生长，在这种情况下，表皮退缩并部分被黏膜取代，其基质被黏液上皮大量侵入，类似于管状腺。
