• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

局部晚期宫颈癌的手术分期:现状与研究进展

Surgical Staging of Locally Advanced Cervical Cancer: Current Status and Research Progress.

作者信息

Zhang He, Kong Weimin, Chen Shuning, Zhao Xiaoling, Luo Dan, Xie Yunkai

机构信息

Department of Gynecological Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing, China.

出版信息

Front Oncol. 2022 Jul 6;12:940807. doi: 10.3389/fonc.2022.940807. eCollection 2022.

DOI:10.3389/fonc.2022.940807
PMID:35875158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9296854/
Abstract

Locally advanced cervical cancer (LACC) has large localized lesions, high recurrence and metastasis rate under standard treatment, and low survival rate. The current guidelines still use concurrent radiotherapy as the gold standard of treatment for locally advanced cervical cancer. Several recent studies have shown that surgical staging has higher accuracy in determining metastasis in the para-aortic lymph nodes, bringing survival benefits to some patients. However, the indications for surgical staging and whether surgical staging can improve prognosis are still controversial. We will review the current status and research progress of surgical staging for locally advanced cervical cancer.

摘要

局部晚期宫颈癌(LACC)具有较大的局部病灶,在标准治疗下复发和转移率高,生存率低。目前的指南仍将同步放疗作为局部晚期宫颈癌的治疗金标准。最近的几项研究表明,手术分期在确定腹主动脉旁淋巴结转移方面具有更高的准确性,给一些患者带来了生存益处。然而,手术分期的适应证以及手术分期是否能改善预后仍存在争议。我们将综述局部晚期宫颈癌手术分期的现状和研究进展。

相似文献

1
Surgical Staging of Locally Advanced Cervical Cancer: Current Status and Research Progress.局部晚期宫颈癌的手术分期:现状与研究进展
Front Oncol. 2022 Jul 6;12:940807. doi: 10.3389/fonc.2022.940807. eCollection 2022.
2
How should we stage and tailor treatment strategy in locally advanced cervical cancer? Imaging versus para-aortic surgical staging.我们应如何对局部晚期宫颈癌进行分期并制定个体化治疗策略?影像学分期与主动脉旁淋巴结手术分期的比较
Int J Gynecol Cancer. 2020 Sep;30(9):1434-1443. doi: 10.1136/ijgc-2020-001351. Epub 2020 Aug 11.
3
The impact of pre-therapy extraperitoneal surgical staging on the evaluation and treatment of patients with locally advanced cervical cancer.治疗前腹膜外手术分期对局部晚期宫颈癌患者评估和治疗的影响。
Eur J Gynaecol Oncol. 2001;22(5):325-30.
4
Laparoscopic Debulking of Enlarged Pelvic Nodes during Surgical Para-aortic Staging in Locally Advanced Cervical Cancer: A Retrospective Comparative Cohort Study.腹腔镜下局部晚期宫颈癌手术性腹主动脉旁分期时肿大盆腔淋巴结切除术:一项回顾性对比队列研究。
J Minim Invasive Gynecol. 2022 Jan;29(1):103-113. doi: 10.1016/j.jmig.2021.06.027. Epub 2021 Jul 1.
5
Survival effect of laparoscopic para-aortic staging in locally advanced cervical cancer: a retrospective cohort analysis.腹腔镜下腹主动脉旁分期对局部晚期宫颈癌的生存影响:一项回顾性队列分析。
BJOG. 2017 Jun;124(7):1089-1094. doi: 10.1111/1471-0528.14492. Epub 2017 Jan 27.
6
Robot-assisted laparoscopic transperitoneal infrarenal lymphadenectomy in patients with locally advanced cervical cancer by single docking: Do we need a backup procedure?单对接机器人辅助腹腔镜经腹膜后入路肾下淋巴结清扫术治疗局部晚期宫颈癌:我们是否需要备用手术方案?
J Robot Surg. 2018 Mar;12(1):49-58. doi: 10.1007/s11701-017-0685-1. Epub 2017 Mar 2.
7
Should the Presence of Metastatic Para-Aortic Lymph Nodes in Locally Advanced Cervical Cancer Lead to More Aggressive Treatment Strategies?局部晚期宫颈癌中转移性主动脉旁淋巴结的存在是否应导致更积极的治疗策略?
J Minim Invasive Gynecol. 2017 May-Jun;24(4):609-616. doi: 10.1016/j.jmig.2017.01.016. Epub 2017 Feb 1.
8
Feasibility of Laparoscopic Para-Aortic Lymphadenectomy for Locally Advanced Cervical Cancer.腹腔镜下盆腔外主动脉旁淋巴结切除术治疗局部晚期宫颈癌的可行性。
JSLS. 2022 Jan-Mar;26(1). doi: 10.4293/JSLS.2021.00096.
9
Para-aortic plus pelvic lymphadenectomy in locally advanced cervical cancer: A single institutional experience.广泛性子宫切除术加盆腔淋巴结切除术治疗局部晚期宫颈癌:单中心经验。
Eur J Obstet Gynecol Reprod Biol. 2019 May;236:79-83. doi: 10.1016/j.ejogrb.2019.02.033. Epub 2019 Mar 12.
10
Added value of para-aortic surgical staging compared to F-FDG PET/CT on the external beam radiation field for patients with locally advanced cervical cancer: An ONCO-GF study.与外部束辐射野 F-FDG PET/CT 相比,局部晚期宫颈癌患者腹主动脉旁手术分期的附加价值:ONCO-GF 研究。
Eur J Surg Oncol. 2020 May;46(5):883-887. doi: 10.1016/j.ejso.2019.11.496. Epub 2019 Nov 11.

引用本文的文献

1
Endostar and chemoradiotherapy for advanced cervical cancer: comparing efficacy and prognosis.恩度与放化疗联合治疗晚期宫颈癌:疗效与预后比较
Am J Transl Res. 2025 Feb 15;17(2):1388-1401. doi: 10.62347/PJVO5304. eCollection 2025.
2
Opportunities to advance cervical cancer prevention and care.推进宫颈癌预防与护理的机遇。
Tumour Virus Res. 2024 Dec;18:200292. doi: 10.1016/j.tvr.2024.200292. Epub 2024 Oct 25.
3
Drug development in LMICs: could the emerging Indian model usher the southeast Asian region?低收入和中等收入国家的药物研发:新兴的印度模式能否引领东南亚地区?
Lancet Reg Health Southeast Asia. 2024 Aug 16;29:100464. doi: 10.1016/j.lansea.2024.100464. eCollection 2024 Oct.
4
The Role of Lymph Node Downstaging Following Neoadjuvant Treatment in a Group of Patients with Advanced Stage Cervical Cancer.新辅助治疗后淋巴结降期在一组晚期宫颈癌患者中的作用。
Medicina (Kaunas). 2024 May 26;60(6):871. doi: 10.3390/medicina60060871.
5
Lymph node dissection before initial treatment for locally advanced cervical cancer: A systematic review and meta-analysis.局部晚期宫颈癌初始治疗前的淋巴结清扫术:系统评价和荟萃分析。
Biomol Biomed. 2024 Oct 17;24(6):1463-1469. doi: 10.17305/bb.2024.10591.
6
A triple-drug combination induces apoptosis in cervical cancer-derived cell lines.一种三联药物组合可诱导宫颈癌衍生细胞系发生凋亡。
Front Oncol. 2023 May 8;13:1106667. doi: 10.3389/fonc.2023.1106667. eCollection 2023.
7
inhibits cervical cancer cell proliferation, migration, and invasion via miR-195-5p/LOXL2 axis.通过miR-195-5p/LOXL2轴抑制宫颈癌细胞的增殖、迁移和侵袭。
Toxicol Res (Camb). 2022 Aug 30;11(5):804-811. doi: 10.1093/toxres/tfac058. eCollection 2022 Oct.

本文引用的文献

1
Cancer statistics, 2022.癌症统计数据,2022 年。
CA Cancer J Clin. 2022 Jan;72(1):7-33. doi: 10.3322/caac.21708. Epub 2022 Jan 12.
2
Current Status and Progress in the Treatment of Lower Limb Lymphedema After Treatment of Gynecological Oncology.妇科肿瘤治疗后下肢淋巴水肿的治疗现状及进展
Lymphat Res Biol. 2022 Jun;20(3):308-314. doi: 10.1089/lrb.2021.0035. Epub 2021 Oct 25.
3
Para-aortic lymphadenectomy in abnormal common iliac bifurcation.异常髂总动脉分叉处的主动脉旁淋巴结清扫术
Int J Gynecol Cancer. 2021 Aug;31(8):1194. doi: 10.1136/ijgc-2021-002748.
4
Transperitoneal versus extraperitoneal laparoscopic aortic lymph nodal staging for locally advanced cervical cancer: A systematic review and meta-analysis.经腹腔与经腹膜外腹腔镜下主动脉淋巴结分期治疗局部晚期宫颈癌的系统评价和荟萃分析。
Eur J Surg Oncol. 2021 Sep;47(9):2256-2264. doi: 10.1016/j.ejso.2021.04.036. Epub 2021 May 1.
5
Surgical versus clinical staging prior to primary chemoradiation in patients with cervical cancer FIGO stages IIB-IVA: oncologic results of a prospective randomized international multicenter (Uterus-11) intergroup study.在宫颈癌国际多中心前瞻性随机分组研究(Uterus-11)中,FIGO 分期 IIB-IVA 期宫颈癌患者行根治性放化疗前手术分期与临床分期的对比:肿瘤学结果。
Int J Gynecol Cancer. 2020 Dec;30(12):1855-1861. doi: 10.1136/ijgc-2020-001973.
6
British Gynaecological Cancer Society (BGCS) cervical cancer guidelines: Recommendations for practice.英国妇科癌症协会(BGCS)宫颈癌指南:实践建议。
Eur J Obstet Gynecol Reprod Biol. 2021 Jan;256:433-465. doi: 10.1016/j.ejogrb.2020.08.020. Epub 2020 Sep 29.
7
Prophylactic Extended-Field Irradiation in Patients With Cervical Cancer: A Literature Review.宫颈癌患者的预防性扩大野照射:文献综述
Front Oncol. 2020 Oct 2;10:579410. doi: 10.3389/fonc.2020.579410. eCollection 2020.
8
How should we stage and tailor treatment strategy in locally advanced cervical cancer? Imaging versus para-aortic surgical staging.我们应如何对局部晚期宫颈癌进行分期并制定个体化治疗策略?影像学分期与主动脉旁淋巴结手术分期的比较
Int J Gynecol Cancer. 2020 Sep;30(9):1434-1443. doi: 10.1136/ijgc-2020-001351. Epub 2020 Aug 11.
9
Laparoscopic aortic lymphadenectomy in left-sided inferior vena cava.左侧下腔静脉的腹腔镜主动脉淋巴结切除术。
Int J Gynecol Cancer. 2020 Sep;30(9):1462-1463. doi: 10.1136/ijgc-2020-001469. Epub 2020 Jun 25.
10
Prognostic Value and Therapeutic Implication of Laparoscopic Extraperitoneal Paraaortic Staging in Locally Advanced Cervical Cancer: A Spanish Multicenter Study.腹腔镜腹膜外主动脉旁分期在局部晚期宫颈癌中的预后价值及治疗意义:一项西班牙多中心研究
Ann Surg Oncol. 2020 Aug;27(8):2829-2839. doi: 10.1245/s10434-020-08329-5. Epub 2020 Mar 9.