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全脊椎切除术治疗术后慢性骨髓炎:一例报告

Total spondylectomy in the treatment of postoperative chronic osteomyelitis: a case report.

作者信息

Fernández-Maza Beatriz, Sánchez-Márquez José Miguel, Talavera-Buedo Gloria, Sánchez Javier, Fernández-Baíllo Nicomedes

机构信息

Department of Orthopedic Surgery, Puerta de Hierro University Hospital, Madrid, Spain.

Section of Spine and Spinal Cord Surgery, Department of Orthopedic Surgery, HM Sanchinarro University Hospital, Madrid, Spain.

出版信息

J Spine Surg. 2022 Jun;8(2):288-295. doi: 10.21037/jss-22-14.

Abstract

BACKGROUND

Infection of the spine after surgical procedures is one of the most dreaded complications of spinal fusion surgery. Treatment goals are to eradicate the necrotic and infected tissue and to obtain a correct spinal profile. Traditionally many authors have recommended the posterolateral or double approach, anterior and posterior. Total spondylectomy is a surgical procedure traditionally used to treat primary and metastatic tumors. The use of this surgical procedure in treatment of chronic vertebral osteomyelitis is not clearly defined in literature.

CASE DESCRIPTION

This case involved a 66-year-old female patient with a history of T9-S1 instrumentation after several surgeries, who developed chronic osteomyelitis of T8-T9 with extensive destruction of the vertebral body and severe thoracic kyphosis. After targeted antibiotic therapy, total spondylectomy of T8-T9 was performed according to the Tomita technique. Necrotic and infected tissues were removed proceeding as if it were chronic osteomyelitis of long bones and performing resection with clear margins, that is, applying the criteria of oncological surgery to this chronic infection. After resection, the sagittal plane is reconstructed in the affected segment, restoring the normal distance between the two healthy vertebrae and the mechanical stability of the spine.

CONCLUSIONS

Total spondylectomy in the treatment of extensive infectious lesions with a mechanical component allows performing resection of infected and necrotic tissue along with biological and mechanical reconstruction. In our case, the complete resection of the infected bone and soft tissues achieved good outcome without complications. We propose total spondylectomy as a reasonable treatment option in complicated spondylodiscitis progressing to extensive chronic osteomyelitis and compromising spinal stability due to a significant loss of bone material.

摘要

背景

脊柱手术后感染是脊柱融合手术最可怕的并发症之一。治疗目标是清除坏死和感染组织,并获得正确的脊柱外形。传统上,许多作者推荐采用后外侧或前后联合双入路。全椎体切除术是一种传统上用于治疗原发性和转移性肿瘤的手术方法。该手术方法在慢性椎体骨髓炎治疗中的应用在文献中尚无明确界定。

病例描述

本病例为一名66岁女性患者,既往有多次手术史,曾行T9 - S1内固定术,现发生T8 - T9慢性骨髓炎,椎体广泛破坏,伴有严重的胸椎后凸畸形。在进行针对性抗生素治疗后,根据Tomita技术对T8 - T9行全椎体切除术。如同处理长骨慢性骨髓炎一样,清除坏死和感染组织,并进行切缘清晰的切除,即对这种慢性感染应用肿瘤外科手术标准。切除后,对受累节段进行矢状面重建,恢复两个健康椎体之间的正常距离以及脊柱的力学稳定性。

结论

对于伴有力学因素的广泛感染性病变,全椎体切除术可在切除感染和坏死组织的同时进行生物学和力学重建。在我们的病例中,感染骨和软组织的完全切除取得了良好效果,且无并发症发生。我们建议,对于进展为广泛慢性骨髓炎并因大量骨质丢失而损害脊柱稳定性的复杂脊椎间盘炎,全椎体切除术是一种合理的治疗选择。

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本文引用的文献

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Outcomes of multilevel vertebrectomy for spondylodiscitis.多节段脊椎切除术治疗脊椎炎的结果。
Spine J. 2019 Feb;19(2):285-292. doi: 10.1016/j.spinee.2018.06.361. Epub 2018 Aug 3.

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