Zheng R S, Sun K X, Zhang S W, Zeng H M, Zou X N, Chen R, Gu X Y, Wei W W, He J
Office for Cancer Registry, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Cancer Research Institute, Cancer Hospital, Xinjiang Medical University, Urumqi 830011, China.
Zhonghua Zhong Liu Za Zhi. 2019 Jan 23;41(1):19-28. doi: 10.3760/cma.j.issn.0253-3766.2019.01.005.
Data from local cancer registries were pooled to estimate cancer incidence and mortality in China, 2015. Data submitted from 501 cancer registries were checked & evaluated according to the criteria of data quality control, and 368 registries' data were qualified for the final analysis. Data were stratified by area (urban/rural), sex, age group and cancer sites, and combined with national population data to estimate cancer incidence and mortality in China, 2015. Chinese population census in 2000 and Segi's population were used for age-standardized. Total population covered by 368 cancer registries were 309 553 499 (148 804 626 in urban and 160 748 873 in rural areas). The percentage of morphologically verified cases (MV) and the percentage of death certificate-only cases (DCO) accounted for 69.34% and 2.09%, respectively, and the mortality to incidence ratio was 0.61. About 3 929 000 new cancer cases were reported in 2015 and the crude incidence rate was 285.83 per 100 000 population (males and females were 305.47 and 265.21 per 100 000 population). Age-standardized incidence rates by Chinese standard population (ASIRC) and by world standard population (ASIRW) were 190.64 and 186.39 per 100 000 population, respectively, with the cumulative incidence rate (0-74 age years old) of 21.44%. The cancer incidence and ASIRC were 304.96/100 000 and 196.09/100 000 in urban areas and 261.40/100 000 and 182.70/100 000 in rural areas, respectively. About 2 338 000 cancer deaths were reported in 2015 and the cancer mortality was 170.05/100 000 (210.10/100 000 in males and 128.00/100 000 in females). Age-standardized mortality rates by Chinese standard population (ASMRC) and by world standard population (ASMRW) were 106.72/100 000 and 105.84/100 000, respectively, with the cumulative incidence rate (0-74 age years old) of 11.94%. The cancer mortality and ASMRC were 172.61/100 000 and 103.65/100 000 in urban areas and 166.79/100 000 and 110.76/100 000 in rural areas, respectively. The most common cancer cases including lung, gastric, colorectal, liver and female breast, the top 10 cancer incidence accounted for about 76.70% of all cancer new cases. The most common cancer deaths including lung, liver, gastric, esophageal and colorectal, the top 10 cancer deaths accounted for about 83.00% of all cancer deaths. The burden of cancer showed a continuous upward trend in China. Cancer prevention and control faces the problem of the disparity in different areas and different cancer burden between men and women. The cancer pattern in China presents the coexistence of the cancer patterns in developed and developing countries. The situation of cancer prevention and control is still serious in China.
汇总来自中国各地癌症登记处的数据,以估算2015年中国的癌症发病率和死亡率。按照数据质量控制标准,对来自501个癌症登记处提交的数据进行了检查和评估,其中368个登记处的数据符合最终分析要求。数据按地区(城市/农村)、性别、年龄组和癌症部位进行分层,并与全国人口数据相结合,以估算2015年中国的癌症发病率和死亡率。采用2000年中国人口普查数据和世标人口对数据进行年龄标准化。368个癌症登记处覆盖的总人口为309553499人(城市地区148804626人,农村地区160748873人)。形态学确诊病例(MV)的比例和仅死亡证明病例(DCO)的比例分别为69.34%和2.09%,死亡率与发病率之比为0.61。2015年报告了约392.9万例新发癌症病例,粗发病率为每10万人口285.83例(男性和女性分别为每10万人口305.47例和265.21例)。按中国标准人口计算的年龄标准化发病率(ASIRC)和按世界标准人口计算的年龄标准化发病率(ASIRW)分别为每10万人口190.64例和186.39例,累积发病率(0至74岁)为21.44%。城市地区癌症发病率和ASIRC分别为304.96/10万和196.09/10万,农村地区分别为261.40/10万和182.70/10万。2015年报告了约233.8万例癌症死亡病例,癌症死亡率为170.05/10万(男性为210.10/10万,女性为128.00/10万)。按中国标准人口计算的年龄标准化死亡率(ASMRC)和按世界标准人口计算的年龄标准化死亡率(ASMRW)分别为每10万人口106.72例和105.84例,累积发病率(0至74岁)为11.94%。城市地区癌症死亡率和ASMRC分别为172.61/10万和103.65/10万,农村地区分别为166.79/10万和110.76/10万。最常见的癌症病例包括肺癌、胃癌、结直肠癌、肝癌和女性乳腺癌,前10位癌症发病率约占所有癌症新发病例的76.70%。最常见的癌症死亡包括肺癌、肝癌、胃癌、食管癌和结直肠癌,前10位癌症死亡约占所有癌症死亡的83.00%。中国癌症负担呈持续上升趋势。癌症防治面临不同地区以及男女之间癌症负担差异的问题。中国的癌症模式呈现出发达国家和发展中国家癌症模式并存的情况。中国癌症防治形势依然严峻。