Roy-Byrne P P, Rubinow D R, Gwirtsman H, Hoban M C, Grover G N
Neuropsychobiology. 1986;16(2-3):61-3. doi: 10.1159/000118298.
There were no significant differences in post-dexamethasone cortisol between the follicular and luteal phase of the menstrual cycle in both women with premenstrual syndrome (PMS) and control subjects tested on these two occasions. Within each menstrual cycle phase, there were also no differences in post-dexamethasone cortisol between the two groups. In a second group of control subjects tested on a single occasion, post-dexamethasone cortisol values were higher when subjects were tested in the middle 2 weeks of the menstrual cycle compared with the first and last weeks of the cycle. This phenomenon, possibly due to estrogen effects, suggests that post-dexamethasone cortisol should be assessed weekly in women with PMS to determine whether they also manifest this normally observed menstrual cycle phase-related pattern, or whether it is absent, reflecting a reproductive endocrine abnormality in this patient group.
在经前综合征（PMS）女性和接受这两次测试的对照受试者中，月经周期的卵泡期和黄体期之间，地塞米松后皮质醇水平无显著差异。在每个月经周期阶段内，两组之间的地塞米松后皮质醇水平也无差异。在另一组仅接受一次测试的对照受试者中，与月经周期的第一周和最后一周相比，在月经周期中间2周进行测试时，地塞米松后皮质醇值更高。这种可能由雌激素作用引起的现象表明，对于PMS女性，应每周评估地塞米松后皮质醇水平，以确定她们是否也表现出这种通常观察到的与月经周期阶段相关的模式，或者是否不存在这种模式，这反映了该患者群体存在生殖内分泌异常。
