Regeneration and Stem Cell Biology Lab, Centre for Molecular and Nanomedical Sciences, International Research Centre, Sathyabama Institute of Science and Technology, Chennai, Tamilnadu, India.
College of Pharmacy, University of Georgia, Athens, Georgia, USA.
Microsc Res Tech. 2022 Nov;85(11):3484-3494. doi: 10.1002/jemt.24205. Epub 2022 Jul 25.
Microscope is a device used for the visualization of tiny objects which are not visible to the naked eye. Traditional microscopes have been crucial for the advancement of contemporary science and medicine. Recent advancements in the field of microscopy have fueled its exponential growth rate. However, due to their expensive cost and complicated structure, modern microscopes remain inaccessible to the majority of the public. Nonetheless, the foldscope paper microscope has made it possible for anyone to explore and understand the world of microbes and organisms. In this review, we have listed foldscope-based research projects in various domains, as well as their key properties when compared to traditional research microscopes. In addition, we have briefly explored the impact of a foldscope microscope on public health, clinical diagnostics, forensic science, agriculture, basic science, developmental biology, and education. Moreover, the major drawbacks of paper microscopes and the current steps being taken to upgrade foldscope and its features are discussed in this review. Finally, we have concluded with our perspective that the microscope may be updated to imitate the advancement of a conventional microscope. RESEARCH HIGHLIGHTS: The foldscope, a low-cost instrument for studying the microscopic world. Foldscope applications were compared to conventional microscopes in many sectors. The foldscope microscope's existing limitations and potential prospects are highlighted.
显微镜是一种用于观察肉眼无法看到的微小物体的设备。传统显微镜对当代科学和医学的发展至关重要。显微镜领域的最新进展推动了其指数级增长。然而，由于其昂贵的成本和复杂的结构，现代显微镜仍然无法为大多数公众所接受。尽管如此，折叠显微镜使得任何人都能够探索和理解微生物和生物体的世界。在这篇综述中，我们列出了基于折叠显微镜的各个领域的研究项目，以及它们与传统研究显微镜相比的关键特性。此外，我们还简要探讨了折叠显微镜对公共卫生、临床诊断、法医学、农业、基础科学、发育生物学和教育的影响。此外，本文还讨论了纸显微镜的主要缺点以及为改进折叠显微镜及其功能而采取的当前步骤。最后，我们得出结论，显微镜可能会更新，以模仿传统显微镜的进步。研究亮点：折叠显微镜，一种用于研究微观世界的低成本仪器。在许多领域将折叠显微镜的应用与传统显微镜进行了比较。突出了折叠显微镜的现有局限性和潜在前景。
