原发性甲状腺黏液纤维肉瘤：一例报告并文献复习
Primary thyroid gland myxofibrosarcoma: a case report and review of the literature.
作者信息
Stylianidi Maria Chara, Haeberle Lena, Schott Matthias, Mori Yuriko, Antke Christina, Giesel Frederick Lars, Antoch Gerald, Esposito Irene, Knoefel Wolfram Trudo, Krieg Andreas
机构信息
Department of Surgery (A), Medical Faculty, Heinrich-Heine-University and University Hospital Duesseldorf, Moorenstr. 5, Bldg. 12.46, 40225, Duesseldorf, Germany.
Institute of Pathology, Medical Faculty, Heinrich-Heine-University and University Hospital Duesseldorf, Duesseldorf, Germany.
出版信息
Surg Case Rep. 2022 Jul 25;8(1):139. doi: 10.1186/s40792-022-01496-5.
BACKGROUND
Myxofibrosarcoma is a common soft tissue sarcoma of the extremities, which occurs very rarely in the thyroid gland.
CASE PRESENTATION
We report the case of a 61-year-old male who presented with a swelling of the left side of the neck and a newly emerged hoarseness. Ultrasound depicted a hypoechoic thyroid nodule with microcalcifications that was highly suspicious for malignancy. He underwent a left hemithyroidectomy. Histopathological examination and immunohistochemical studies revealed a myxofibrosarcoma of the thyroid gland.
CONCLUSION
Myxofibrosarcoma of the thyroid gland is extremely rare. The diagnosis is based on histopathological features. Radical surgery achieving tumor-free resection margins remains the only chance for cure. However, the role of radiotherapy and/or chemotherapy is still under debate. Due to their high tendency for locoregional recurrence, a close follow-up after surgery is mandatory.
背景
黏液纤维肉瘤是四肢常见的软组织肉瘤，极少发生于甲状腺。
病例报告
我们报告一例61岁男性，其表现为左侧颈部肿胀及新发声音嘶哑。超声显示一个伴有微钙化的低回声甲状腺结节，高度怀疑为恶性。他接受了左侧甲状腺叶切除术。组织病理学检查和免疫组化研究显示为甲状腺黏液纤维肉瘤。
结论
甲状腺黏液纤维肉瘤极为罕见。诊断基于组织病理学特征。实现切缘无肿瘤的根治性手术仍然是治愈的唯一机会。然而，放疗和/或化疗的作用仍存在争议。由于其局部区域复发倾向高，术后密切随访是必要的。
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