Dong Jinhui, Li Qi, Wang Xiaofei, Fan Yubo
Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.
Bioengineering (Basel). 2022 Jul 11;9(7):304. doi: 10.3390/bioengineering9070304.
The monitoring of intracranial pressure (ICP) is essential for the detection and treatment of most craniocerebral diseases. Invasive methods are the most accurate approach to measure ICP; however, these methods are prone to complications and have a limited range of applications. Therefore, non-invasive ICP measurement is preferable in a range of scenarios. The current non-invasive ICP measurement methods comprise fluid dynamics, and ophthalmic, otic, electrophysiological, and other methods. This article reviews eight methods of non-invasive estimation of ICP from ocular measurements, namely optic nerve sheath diameter, flash visual evoked potentials, two-depth transorbital Doppler ultrasonography, central retinal venous pressure, optical coherence tomography, pupillometry, intraocular pressure measurement, and retinal arteriole and venule diameter ratio. We evaluated and presented the indications and main advantages and disadvantages of these methods. Although these methods cannot completely replace invasive measurement, for some specific situations and patients, non-invasive measurement of ICP still has great potential.
颅内压（ICP）监测对于大多数颅脑疾病的检测和治疗至关重要。有创方法是测量ICP最准确的途径；然而，这些方法容易引发并发症且应用范围有限。因此，在一系列情况下，无创ICP测量更可取。当前的无创ICP测量方法包括流体动力学、眼科、耳科、电生理及其他方法。本文综述了通过眼部测量无创估计ICP的八种方法，即视神经鞘直径、闪光视觉诱发电位、双深度经眶多普勒超声检查、视网膜中央静脉压、光学相干断层扫描、瞳孔测量、眼压测量以及视网膜动静脉直径比。我们评估并介绍了这些方法的适应症以及主要优缺点。尽管这些方法不能完全取代有创测量，但对于某些特定情况和患者，无创ICP测量仍具有巨大潜力。
