Haik B G, Dunleavy S A, Cooke C, Ellsworth R M, Abramson D H, Smith M E, Karcioglu Z A
Ophthalmology. 1987 Apr;94(4):367-70. doi: 10.1016/s0161-6420(87)33437-2.
Anterior chamber retinoblastoma is a rare clinical entity. The authors have reviewed the records of 1500 patients with retinoblastoma to determine the incidence and prognostic ramifications. Of 30 patients with anterior chamber involvement, 15 were noted on initial examination and 15 during observation after therapy. Despite aggressive multimodality treatment, total response was never achieved and all eyes were eventually lost. Results of pathologic examination showed ciliary body invasion, which was held accountable for the poor response to therapy. Anterior chamber retinoblastoma is a poor prognostic sign which cannot be controlled effectively with current techniques and should be considered an indication for enucleation without delay.
前房视网膜母细胞瘤是一种罕见的临床病症。作者回顾了1500例视网膜母细胞瘤患者的病历，以确定其发病率及对预后的影响。在30例有前房受累的患者中，15例在初次检查时被发现，15例在治疗后的观察期间被发现。尽管采取了积极的多模式治疗，但从未实现完全缓解，最终所有患眼均失明。病理检查结果显示有睫状体侵犯，这被认为是治疗反应不佳的原因。前房视网膜母细胞瘤是预后不良的征象，目前的技术无法有效控制，应立即考虑行眼球摘除术。
