De Francesco Sonia, Pichi Francesco, Lembo Andrea, Mastrangelo Domenico, Paradiso Anna, De Luca Mariacarla, Toti Paolo, Nucci Paolo, Hadjistilianou Theodora
Retinoblastoma Referral Center, University of Siena, Siena, Italy.
Int Ophthalmol. 2014 Aug;34(4):967-70. doi: 10.1007/s10792-014-9905-0. Epub 2014 Jan 30.
This case report highlights the usefulness of Ultrasound Biomicroscopy (UBM) in a case of retinoblastoma which showed massive anterior chamber involvement after treatment with intra-arterial chemotherapy. UBM was used to document tumour pseudohypopion, cells in the aqueous humor, implanted clusters of cells on the corneal endothelium, iris nodules, lens capsule deposits and ciliary body invasion. The UBM data, compared with the histopathologic analysis, performed on eye tissue, after enucleation of the affected eye, revealed a significant concordance. UBM may represent an important diagnostic tool in retinoblastoma, when the decision about enucleation of the eye must be made in the absence of histopathologic data.
本病例报告强调了超声生物显微镜（UBM）在一例视网膜母细胞瘤病例中的应用价值，该病例在接受动脉内化疗后出现大量前房受累。UBM用于记录肿瘤性假前房积脓、房水中的细胞、角膜内皮上植入的细胞簇、虹膜结节、晶状体囊膜沉积物和睫状体侵犯。与对患眼摘除后眼组织进行的组织病理学分析相比，UBM数据显示出显著的一致性。当在没有组织病理学数据的情况下必须做出患眼摘除的决定时，UBM可能是视网膜母细胞瘤的一种重要诊断工具。
