Ma Xing, Hua Marti Z, Ji Chao, Zhang Jing, Shi Rui, Xiao Yabing, Liu Xiaojing, He Xiahong, Zheng Wenjie, Lu Xiaonan
Laboratory for Quality Control and Traceability of Food, Tianjin Normal University, Tianjin 300387, China.
The Animal, Plant & Foodstuff Inspection Center of Tianjin Customs, Tianjin 300387, China.
Analyst. 2022 Aug 8;147(16):3628-3633. doi: 10.1039/d2an00752e.
Traditional Chinese herbal medicines are subject to heavy metal contamination. Standard detection methods are too complicated, time-consuming, and expensive for routine analysis, so low-cost methods are in high demand for rapid on-site screening. This study reports a high-sensitivity X-ray fluorescence (HS-XRF) method to determine As, Pb, and Cd residues simultaneously in herbal medicines. It couples monochromatic excitation energy dispersive X-ray fluorescence spectrometry and the fast fundamental parameters method. Each test takes only 10-30 min and costs 1/10th to 1/5th of the standard method. The detection limits, precision and accuracy were evaluated using different approaches, and application notes in practice are also proposed. This study is the first attempt to establish and evaluate HS-XRF in analyzing multiple heavy metals in herbal medicines. This rapid screening method would promote the testing efficiency and thus improve the monitoring of heavy metal contamination in herbal medicines.
传统中药存在重金属污染问题。标准检测方法对于常规分析来说过于复杂、耗时且昂贵，因此低成本方法对于快速现场筛查的需求很高。本研究报告了一种高灵敏度X射线荧光（HS-XRF）方法，用于同时测定中药中的砷、铅和镉残留量。它结合了单色激发能量色散X射线荧光光谱法和快速基本参数法。每次测试仅需10 - 30分钟，成本仅为标准方法的十分之一到五分之一。使用不同方法评估了检测限、精密度和准确度，并提出了实际应用中的注意事项。本研究是首次尝试建立和评估HS-XRF用于分析中药中的多种重金属。这种快速筛查方法将提高检测效率，从而改善对中药中重金属污染的监测。
