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植入式心脏除颤器在左心室辅助装置患者中的应用:来自国家数据库的见解。

Utilization of Implantable Cardioverter Defibrillators Among Patients with a Left Ventricular Assist Device: Insights From a National Database.

机构信息

Department of Medicine, University of Mississippi Medical Center, Jackson, MS.

Department of Medicine, Forrest General Hospital, Hattiesburg, MS.

出版信息

Curr Probl Cardiol. 2022 Nov;47(11):101334. doi: 10.1016/j.cpcardiol.2022.101334. Epub 2022 Jul 23.

Abstract

The trends of implantable cardioverter defibrillator (ICD) use in patients with a durable left ventricular assist device (LVAD) remain uncertain. We used the National Inpatient Sample to identify hospitalizations between 2009 and 2018 in which patients received a new LVAD or had a pre-existing one. Procedure codes were then used to identify hospitalizations in which a new ICD was implanted. In 34,113 hospitalizations for new and/or replacement LVADs, an ICD was implanted in 1297 (3.8%). The rate of ICD implantation along with an LVAD declined from 2009 to 2018 (annual percent change: -23.2%; P-trend < 0.001). Independent factors associated with concurrent ICD implantation in patients receiving LVAD were younger age, White (compared with Black) race, and in-hospital cardiac arrest. Concurrent ICD implantation was associated with a longer hospital stay (adjusted mean difference: 4.48 days) and higher inflation-adjusted costs (adjusted mean difference: $31,679), but lower in-hospital mortality rates (adjusted odds ratio: 0.29; P < 0.001), compared with LVAD placement alone. Amongst 95,583 hospitalizations of patients with a pre-existing LVAD, an ICD was placed in 616 (0.64%). There was no change in the rate of ICD implantation from 2009 to 2018 in patients with a pre-existing LVAD (annual percent change: -10.34%; P = 0.18).

摘要

植入式心脏复律除颤器 (ICD) 在永久性左心室辅助装置 (LVAD) 患者中的使用趋势仍不确定。我们使用国家住院患者样本,确定了 2009 年至 2018 年期间患者接受新的 LVAD 或存在先前的 LVAD 的住院情况。然后使用程序代码来确定植入新 ICD 的住院情况。在 34113 例新的和/或更换的 LVAD 住院治疗中,有 1297 例(3.8%)植入了 ICD。从 2009 年到 2018 年,植入 ICD 的比率以及 LVAD 的植入率均有所下降(年变化百分比:-23.2%;P 趋势 < 0.001)。在接受 LVAD 的患者中,同时植入 ICD 的独立因素包括年龄较小、白人(与黑人相比)种族和院内心搏骤停。同时植入 ICD 与住院时间延长(调整后的平均差异:4.48 天)和通胀调整后的费用增加(调整后的平均差异:31679 美元)相关,但院内死亡率降低(调整后的优势比:0.29;P < 0.001),与单独植入 LVAD 相比。在 95583 例存在先前 LVAD 的患者的住院治疗中,有 616 例(0.64%)植入了 ICD。在存在先前 LVAD 的患者中,从 2009 年到 2018 年,植入 ICD 的比率没有变化(年变化百分比:-10.34%;P=0.18)。

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