PEDEGO Research Unit, University of Oulu, POB 8000, FIN-90014 Oulu, Finland.
Department of Obstetrics and Gynecology, Medical Research Center Oulu, Oulu University Hospital, POB 10, FIN-90029 Oulu, Finland.
Cells. 2022 Jul 18;11(14):2226. doi: 10.3390/cells11142226.
Bronchoalveolar lavage (BAL) is an important diagnostic and research tool for the investigation of various lung diseases. In addition to inflammatory and epithelial cells, BAL fluid may contain a small number of stromal cells, such as fibroblasts. During the past 30 years, a number of research groups have cultured BAL-derived fibroblasts for several passages in vitro. In addition to fibroblasts, these cultures have been reported to contain fibrocytes, myofibroblasts, and stem cells. We aim to present a summary of studies that have cultured stromal cells from BAL fluid.
支气管肺泡灌洗（BAL）是一种重要的诊断和研究工具，可用于研究各种肺部疾病。除了炎症细胞和上皮细胞外，BAL 液中还可能含有少量基质细胞，如成纤维细胞。在过去的 30 年中，许多研究小组已经在体外对 BAL 衍生的成纤维细胞进行了多次传代培养。除了成纤维细胞外，这些培养物中还报道含有纤维细胞、肌成纤维细胞和干细胞。我们旨在对培养 BAL 液中的基质细胞的研究进行总结。
Zotero 插件