Rodríguez-Cano Ameyalli M, González-Ludlow Isabel, Suárez-Rico Blanca V, Montoya-Estrada Araceli, Piña-Ramírez Omar, Parra-Hernández Sandra B, Reyes-Muñoz Enrique, Estrada-Gutierrez Guadalupe, Calzada-Mendoza Claudia C, Perichart-Perera Otilia
Section for Postgraduate Studies and Research, Higher School of Medicine, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón s/n, Casco de Santo Tomas, Miguel Hidalgo, Mexico City 11340, Mexico.
Nutrition and Bioprogramming Coordination, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Montes Urales 800, Lomas de Virreyes, Miguel Hidalgo, Mexico City 11000, Mexico.
Antioxidants (Basel). 2022 Jul 21;11(7):1415. doi: 10.3390/antiox11071415.
Ultra-processed food (UPF) consumption during gestation may lead to increased oxidative stress (OS) and could affect pregnancy outcomes. This study aims to evaluate the association of UPF consumption during pregnancy with circulating levels of OS markers. Diet was assessed (average of three assessments) in 119 pregnant women enrolled in the OBESO perinatal cohort (Mexico), obtaining quantitative data and the percentage of energy that UPFs (NOVA) contributed to the total diet. Sociodemographic, clinical (pregestational body-mass index and gestational weight gain) and lifestyle data were collected. Maternal circulating levels of OS markers (malondialdehyde (MDA), protein carbonylation (PC), and total antioxidant capacity (TAC)) were determined at the third trimester of pregnancy. Adjusted linear regression models were performed to analyze the association between UPFs and OS markers. UPFs represented 27.99% of the total energy intake. Women with a lower UPF consumption (<75 percentile°) presented a higher intake of fiber, ω-3, ω-6, and a lower ω-6/3 ratio. Linear regression models showed that UPFs were inversely associated with TAC and MDA. Fiber intake was associated with PC. UPF intake during pregnancy may result in an increase in oxidative stress. When providing nutrition care, limiting or avoiding UPFs may be an intervention strategy that could promote a better antioxidant capacity in the body.
孕期食用超加工食品（UPF）可能会导致氧化应激（OS）增加，并可能影响妊娠结局。本研究旨在评估孕期UPF摄入量与循环中OS标志物水平之间的关联。对纳入OBESO围产期队列研究（墨西哥）的119名孕妇的饮食进行了评估（三次评估的平均值），获取了定量数据以及UPF（新北欧食品分类法）在总饮食中所占的能量百分比。收集了社会人口统计学、临床（孕前体重指数和孕期体重增加）及生活方式数据。在妊娠晚期测定孕妇循环中OS标志物（丙二醛（MDA）、蛋白质羰基化（PC）和总抗氧化能力（TAC））的水平。采用校正线性回归模型分析UPF与OS标志物之间的关联。UPF占总能量摄入的27.99%。UPF摄入量较低（<第75百分位数）的女性膳食纤维、ω-3、ω-6的摄入量较高，ω-6/ω-3比值较低。线性回归模型显示，UPF与TAC和MDA呈负相关。膳食纤维摄入量与PC相关。孕期摄入UPF可能会导致氧化应激增加。在提供营养护理时，限制或避免UPF可能是一种有助于提高机体抗氧化能力的干预策略。
