Catalano Alessia, Ceramella Jessica, Iacopetta Domenico, Mariconda Annaluisa, Scali Elisabetta, Bonomo Maria Grazia, Saturnino Carmela, Longo Pasquale, Aquaro Stefano, Sinicropi Maria Stefania
Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, 70126 Bari, Italy.
Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Cosenza, Italy.
Antibiotics (Basel). 2022 Jul 14;11(7):947. doi: 10.3390/antibiotics11070947.
These days, most of our attention has been focused on the COVID-19 pandemic, and we have often neglected what is happening in the environment. For instance, the bacterium re-emerged as a plant pathogen of global importance in 2013 when it was first associated with an olive tree disease epidemic in Italy, called Olive Quick Decline Syndrome (OQDS), specifically caused by subspecies ST53, which affects the Salento olive trees (Apulia, South-East Italy). This bacterium, transmitted by the insect is negatively reshaping the Salento landscape and has had a very high impact in the production of olives, leading to an increase of olive oil prices, thus new studies to curb this bacterium are urgently needed. Thidiazuron (TDZ), a diphenylurea (-phenyl-1,2,3-thiadiazol-5-yl urea), has gained considerable attention in recent decades due to its efficient role in plant cell and tissue culture, being the most suitable growth regulator for rapid and effective plant production in vitro. Its biological activity against bacteria, fungi and biofilms has also been described, and the use of this low-cost compound to fight OQDS may be an intriguing idea.
如今，我们大部分注意力都集中在新冠疫情上，常常忽视了环境中正在发生的事情。例如，这种细菌在2013年重新成为一种具有全球重要性的植物病原体，当时它首次与意大利的一种橄榄树疾病流行相关联，这种疾病被称为橄榄快速衰退综合征（OQDS），具体由亚种ST53引起，它影响萨伦托橄榄树（意大利东南部普利亚地区）。这种由昆虫传播的细菌正在对萨伦托的景观产生负面影响，并对橄榄生产造成了非常大的影响，导致橄榄油价格上涨，因此迫切需要开展新的研究来遏制这种细菌。噻苯隆（TDZ），一种二苯脲（-苯基-1,2,3-噻二唑-5-基脲），近几十年来因其在植物细胞和组织培养中的有效作用而备受关注，是体外快速有效植物生产最适合的生长调节剂。它对细菌、真菌和生物膜的生物活性也有描述，使用这种低成本化合物来对抗OQDS可能是一个有趣的想法。
