Szepietowski T, Uzar J
Polim Med. 1986;16(3-4):123-35.
By means of the method divised by the authors two types of capillary dialyzers were used many times: MTS C 1.0 model by Fresenius, membrane thickness 11 mu, and 23-08 model by Travenol, membrane thickness 8 mu. At the fourth use of the Fresenius dialyzers it was found in the studies performed at the start of haemolysis that urea clearanic decreased by 8% on the average. This, with the blood flow of 200 ml/min, was significant statistically (p less than 0.05). In the Travenol dialyzers the decrease was by 18% on the average, while the decrease that was statistically significant was when the dialyzer was used for the second time (p less than 0.05). Creatinine clearance at the fourth use of the Travenol dialyzers decreased by 20% on the average--insignificantly, and in the Fresenius dialyzers it decreased significantly at the second use (p less than 0.01), though at the fourth haemodialysis it decreased by 10% on the average. Clearance of urea and creatinine at the end of haemodialysis decreased more prominently than at the start. This caused an increase in the difference between the start and the end of the dialysis, which in the Travenol dialyzers was made visible as late as at the fourth use of dialyzer. The authors think that the data show the capillary dialyzers can be used three or four times.
费森尤斯公司的MTS C 1.0型号，膜厚度为11微米；以及特拉文诺公司的23 - 08型号，膜厚度为8微米。在第四次使用费森尤斯透析器时，在溶血开始时进行的研究发现，尿素清除率平均下降了8%。在血流量为200毫升/分钟的情况下，这具有统计学意义（p < 0.05）。在特拉文诺透析器中，平均下降率为18%，而具有统计学意义的下降是在透析器第二次使用时（p < 0.05）。特拉文诺透析器第四次使用时肌酐清除率平均下降20%，不显著；而费森尤斯透析器在第二次使用时肌酐清除率显著下降（p < 0.01），不过在第四次血液透析时平均下降了10%。血液透析结束时尿素和肌酐的清除率比开始时下降得更明显。这导致透析开始和结束时的差异增大，在特拉文诺透析器中直到第四次使用透析器时才显现出来。作者认为这些数据表明毛细血管透析器可以使用三到四次。
